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斑贴试验:陷阱与操作

Patch testing: pitfalls and performance.

作者信息

Mowad Christen M

机构信息

Geisinger Medical Center, Danville, Pennsylvania 17821, USA.

出版信息

Curr Opin Allergy Clin Immunol. 2006 Oct;6(5):340-4. doi: 10.1097/01.all.0000244794.03239.8e.

Abstract

PURPOSE OF REVIEW

Contact dermatitis is a common disease process that includes allergic and irritant contact dermatitis. The gold standard for diagnosing allergic contact dermatitis, a type IV delayed hypersensitivity reaction, is patch testing. Patch testing is not a difficult procedure, however, there are several critical components that determine the success of the test: having an appropriate level of suspicion for the diagnosis of allergic contact dermatitis, an adequate threshold for patch testing, the necessary experience to properly interpret the results and to determine their relevance, and the ability to thoroughly educate the patient about the condition.

RECENT FINDINGS

Research shows that patch testing practices differ among individuals and specialties. The level of patch testing education, interest in, and experience with, the procedure can affect the results of the test. Some of these practice differences and how they affect the outcome of patch testing are highlighted.

SUMMARY

Physicians' knowledge and experience with patch testing, their level of interest and access to allergens will determine the performance of this test, the reliability of the results and the benefits gained from this procedure.

摘要

综述目的

接触性皮炎是一种常见的疾病过程,包括过敏性接触性皮炎和刺激性接触性皮炎。诊断过敏性接触性皮炎(一种IV型迟发型超敏反应)的金标准是斑贴试验。斑贴试验并非复杂的操作,然而,有几个关键因素决定了试验的成功:对过敏性接触性皮炎诊断有适当的怀疑程度、进行斑贴试验的足够阈值、正确解读结果并确定其相关性的必要经验,以及向患者全面宣教病情的能力。

最新发现

研究表明,斑贴试验的操作在个体和专业之间存在差异。斑贴试验的教育水平、对该操作的兴趣和经验会影响试验结果。文中强调了其中一些操作差异以及它们如何影响斑贴试验的结果。

总结

医生对斑贴试验的知识和经验、他们的兴趣水平以及获得变应原的途径将决定该试验的实施情况、结果的可靠性以及从该操作中获得的益处。

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