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喉气管狭窄的现代管理

Modern management of laryngotracheal stenosis.

作者信息

Herrington Heather C, Weber Stephen M, Andersen Peter E

机构信息

Department of Otolaryngology and Head and Neck Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon, USA.

出版信息

Laryngoscope. 2006 Sep;116(9):1553-7. doi: 10.1097/01.mlg.0000228006.21941.12.

DOI:10.1097/01.mlg.0000228006.21941.12
PMID:16954977
Abstract

OBJECTIVES

Laryngotracheal stenosis is a complex problem resulting most often from intubation, trauma,or autoimmune disease. Management options include dilation or airway reconstruction including laryngotracheoplasty (LTP), cricotracheal resection (CTR), and tracheal resection (TR). We describe our experience with management of this difficult problem.

STUDY DESIGN

Retrospective chart review of patients treated for laryngotracheal stenosis between January 1995 and July 2005 at an academic, tertiary referral center.

METHODS

A total of 127 patients were treated during the study period. Patients were followed, and hospital records were reviewed.

RESULTS

There were 38 male and 89 female patients with an average age of 55.5 years treated for laryngotracheal stenosis resulting from intubation (64), idiopathic (25) or autoimmune disease (18), radiation (9), trauma (5), prior surgery (4), and relapsing polychondritis (2). Thirty-three percent were treated for grade I stenosis, 44% grade II, 19% grade III, and 4% grade IV. Seventy percent of patients undergoing initial dilation required a subsequent procedure. LTP, CTR, or TR was performed in 43%, 48%, 71%, and 100% of patients with grade I through IV stenosis, respectively. Among 76 patients undergoing LTP, CTR, or TR, 24 (32%) required a subsequent intervention. Among 36 patients treated with primary LTP, CTR, or TR, only 10 (28%) required further therapy. Twenty-two of 35 (63%) tracheostomy-dependent patients were ultimately decannulated. Three patients died in the immediate postoperative period.

CONCLUSIONS

Patients undergoing dilation for laryngotracheal stenosis require multiple procedures. However, major reconstructive procedures are well tolerated and currently represent a viable primary treatment for laryngotracheal stenosis.

摘要

目的

喉气管狭窄是一个复杂的问题,最常见的病因是插管、创伤或自身免疫性疾病。治疗方案包括扩张或气道重建,如喉气管成形术(LTP)、环状气管切除术(CTR)和气管切除术(TR)。我们描述了我们处理这一难题的经验。

研究设计

对1995年1月至2005年7月在一家学术性三级转诊中心接受喉气管狭窄治疗的患者进行回顾性病历审查。

方法

在研究期间共治疗了127例患者。对患者进行随访,并查阅医院记录。

结果

共有38例男性和89例女性患者接受了喉气管狭窄治疗,平均年龄55.5岁,病因包括插管(64例)、特发性(25例)、自身免疫性疾病(18例)、放疗(9例)、创伤(5例)、既往手术(4例)和复发性多软骨炎(2例)。33%的患者为I级狭窄,44%为II级,19%为III级,4%为IV级。70%接受初始扩张治疗的患者需要后续治疗。I至IV级狭窄患者分别有43%、48%、71%和100%接受了LTP、CTR或TR治疗。在接受LTP、CTR或TR治疗的76例患者中,24例(32%)需要后续干预。在接受原发性LTP、CTR或TR治疗的36例患者中,只有10例(28%)需要进一步治疗。35例依赖气管造口术的患者中有22例(63%)最终拔管。3例患者在术后即刻死亡。

结论

接受喉气管狭窄扩张治疗的患者需要多次手术。然而,主要的重建手术耐受性良好,目前是喉气管狭窄可行的主要治疗方法。

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