Angeli Simon I, Kulak Jessica L, Guzmán Jose
Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Laryngoscope. 2006 Sep;116(9):1594-9. doi: 10.1097/01.mlg.0000232495.77308.46.
To identify prognostic factors affecting outcome in lateral tympanoplasty for total or near-total tympanic membrane perforation.
Retrospective case series.
Patients were those presenting with total or near-total tympanic membrane perforation undergoing lateral tympanoplasty from 1999 to 2004. We systematically collected demographic, clinical, audiologic, and outcome information. Student t test was used to determine group differences. Logistic regression analysis was used to examine the relationship between success of grafting (dependent variable) and the independent variables. Multiple regression analysis was used to examine the relationship between postoperative air-bone gap (ABG) and independent variables.
There were seventy-seven cases (58 primary and 19 revision cases) with average follow-up of 17 months. Successful tympanic membrane grafting occurred in 91% of cases. None of the independent variables studied was predictive of the success of graft incorporation (P > .05). The mean preoperative ABG was 29.8 +/- 10 dB and improved to a postoperative ABG of 16.5 +/- 11 dB (P < .001). Smaller preoperative ABG and normal malleus handle were associated with smaller postoperative ABG. In revision cases, mastoidectomy was associated with better functional results.
Successful grafting of near-total and total tympanic membrane perforations occurred in 91% of the cases and was independent of demographic, disease, and technical variables. Disease variables (preoperative ABG and status of malleus handle) had a greater prognostic value on postoperative ABG than other variables. In revision tympanoplasty, mastoidectomy is associated with a better functional outcome.
确定影响全层或近全层鼓膜穿孔行外侧鼓室成形术预后的因素。
回顾性病例系列研究。
研究对象为1999年至2004年期间因全层或近全层鼓膜穿孔而行外侧鼓室成形术的患者。我们系统收集了人口统计学、临床、听力学及预后信息。采用学生t检验确定组间差异。采用逻辑回归分析来检验植皮成功(因变量)与自变量之间的关系。采用多元回归分析来检验术后气骨导差(ABG)与自变量之间的关系。
共77例(58例初次手术,19例翻修手术),平均随访17个月。91%的病例鼓膜植皮成功。所研究的自变量均不能预测植皮成功与否(P > .05)。术前平均ABG为29.8 +/- 10 dB,术后改善至16.5 +/- 11 dB(P < .001)。术前ABG较小及锤骨柄正常与术后较小的ABG相关。在翻修手术病例中,乳突切除术与更好的功能结果相关。
91%的近全层和全层鼓膜穿孔植皮成功,且与人口统计学、疾病及技术变量无关。疾病变量(术前ABG和锤骨柄状态)对术后ABG的预后价值大于其他变量。在翻修鼓室成形术中,乳突切除术与更好的功能结果相关。