Renzelli Cara M, Capretto Neil A
Gateway Rehabilitation Center, Moffett Run Road, Aliquippa, PA 15001, USA.
J Addict Dis. 2006;25(3):97-104. doi: 10.1300/J069v25n03_12.
Research indicates that persons addicted to opiates are likely to relapse following treatment or are at risk of terminating treatment early. The withdrawal experience may be one factor underlying early treatment discharge and several medications, including buprenorphine-naloxone, have been used to reduce withdrawal symptoms during detoxification. This retrospective study sought to determine whether patients who received buprenorphine-naloxone were retained in treatment longer than those who did not receive the medication. Data were collected on 170 patients admitted to the detoxification unit who either received (n = 85) or did not receive (n = 85) the medication. Differences in lengths of stay were found between the groups, thus warranting future research on the usefulness of buprenorphine-naloxone during detoxification and subsequent treatment. The importance of detoxification as an initial phase of treatment in relation to patient retention is discussed.
研究表明，对阿片类药物上瘾的人在治疗后很可能复发，或者有提前终止治疗的风险。戒断体验可能是导致早期治疗中断的一个因素，包括丁丙诺啡-纳洛酮在内的几种药物已被用于减轻戒毒期间的戒断症状。这项回顾性研究旨在确定接受丁丙诺啡-纳洛酮治疗的患者是否比未接受该药物治疗的患者在治疗中停留的时间更长。收集了170名入住戒毒科患者的数据，其中85名接受了该药物治疗，85名未接受该药物治疗。两组之间在住院时间上存在差异，因此有必要对丁丙诺啡-纳洛酮在戒毒及后续治疗中的效用进行进一步研究。文中还讨论了戒毒作为治疗初始阶段对于患者留存率的重要性。
