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放疗联合动脉内灌注化疗对腮腺复发性腺样囊性癌的长期局部控制

Long-term local control of recurrent adenoid cystic carcinoma in the parotid gland with radiotherapy and intraarterial infusion chemotherapy.

作者信息

Terashima Koutarou, Shioyama Yoshiyuki, Nakamura Katsumasa, Ohga Saiji, Nomoto Satoshi, Yamaguchi Toshihiro, Toba Takashi, Yoshitake Tadamasa, Yabuuchi Hidetake, Nakashima Torahiko, Terashima Hiromi, Honda Hiroshi

机构信息

Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, Japan.

出版信息

Radiat Med. 2006 May;24(4):287-91. doi: 10.1007/s11604-005-1567-4.

Abstract

We report a case of postoperative recurrence of adenoid cystic carcinoma in the left parotid gland treated with radiotherapy and arterial infusion chemotherapy. A 52-year-old woman had a history of surgical resection for an adenoid cystic carcinoma arising from the left parotid gland 25 years before. Despite two reoperations for local recurrence after the initial surgery, she had a third local recurrence in the remnant of the left parotid gland. The patient was treated with a concurrent combination of radiotherapy (60 Gy/30F) and intraarterial infusion chemotherapy with carboplatin (750 mg/30 days) from which she obtained a complete response. The patient has remained free of local progression 54 months after treatment. Radiotherapy and arterial infusion chemotherapy is effective treatment for local recurrence of adenoid cystic carcinoma in the head and neck.

摘要

我们报告一例左腮腺腺样囊性癌术后复发患者,采用放疗和动脉灌注化疗进行治疗。一名52岁女性在25年前曾因左腮腺腺样囊性癌接受手术切除。尽管在初次手术后因局部复发进行了两次再次手术,但她在左腮腺残余部位出现了第三次局部复发。该患者接受了放疗(60 Gy/30次分割)和卡铂动脉灌注化疗(750 mg/30天)的联合治疗,获得了完全缓解。治疗后54个月,患者局部无进展。放疗和动脉灌注化疗是治疗头颈部腺样囊性癌局部复发的有效方法。

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