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[大量血脂异常患者:葡聚糖二乙氨基乙基酯治疗的效果]

[A large case load of patients with dyslipidemia: effects of treatment with deae-dextran].

作者信息

Barone A, Frausini G, Ansuini R, Francolini G, Canestrari M, Ultimare R, Pupita F

机构信息

Divisione di Medicina, Ospedale Unificato di Fano-Mondolfo.

出版信息

Clin Ter. 1990 May 31;133(4):239-43.

PMID:1695872
Abstract

The authors report the results of an open trial in 859 dyslipidemic patients, performed with the cooperation of general practitioners, treated with isocaloric diet and daily doses of 3 g deae-dextran for 3 months. Deae-dextran was effective in reducing cholesterol and triglyceride blood levels and in controlling body weight. The drug was very well tolerated and no significant side effects were registered during treatment with deae-dextran.

摘要

作者报告了一项在859名血脂异常患者中进行的开放试验结果,该试验由全科医生合作开展,患者采用等热量饮食,并每日服用3克二乙氨基葡聚糖,为期3个月。二乙氨基葡聚糖在降低血液中胆固醇和甘油三酯水平以及控制体重方面有效。该药物耐受性良好,在使用二乙氨基葡聚糖治疗期间未出现明显副作用。

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