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[人血清中甲胎蛋白的固相免疫酶分析]

[Solid-phase immunoenzyme analysis of alpha-fetoprotein in human blood serum].

作者信息

Shevtsova A I, Demchenko T V, Lapa T V

出版信息

Lab Delo. 1990(5):52-5.

PMID:1695975
Abstract

A test system for enzyme immunoassay of alpha-fetoprotein (AFP) was developed on the basis of the diagnostic agents manufactured by the N. F. Gamaleya Research Institute of Epidemiology and Microbiology. The effect of shielding antibody active centers in sensitization of planes with excessive concentrations of antibodies was detected. The test system was used to measure AFP levels in blood sera of pregnant women. The results may be used for screening pregnant women for the prenatal diagnosis of fetal neural tube.

摘要

基于俄罗斯国家流行病学和微生物学研究所N.F.加马列亚研究所生产的诊断试剂,开发了一种用于甲胎蛋白(AFP)酶免疫测定的检测系统。检测到在使用过量抗体致敏平板时屏蔽抗体活性中心的效果。该检测系统用于测量孕妇血清中的AFP水平。该结果可用于对孕妇进行筛查,以进行胎儿神经管的产前诊断。

相似文献

1
[Solid-phase immunoenzyme analysis of alpha-fetoprotein in human blood serum].[人血清中甲胎蛋白的固相免疫酶分析]
Lab Delo. 1990(5):52-5.
2
[Prenatal detection of open neural tube defects in a mass screening program by determination of alpha-fetoprotein concentration in maternal serum].
Zentralbl Gynakol. 1988;110(3):158-67.
3
Improved reliability of a serum alpha-fetoprotein enzyme immunoassay compared with a radioimmunoassay.与放射免疫测定法相比,血清甲胎蛋白酶免疫测定法的可靠性得到提高。
Isr J Med Sci. 1986 Mar-Apr;22(3-4):215-9.
4
Prenatal diagnosis of neural tube defects. VIII. The importance of serum alpha-fetoprotein screening in diabetic pregnant women.神经管缺陷的产前诊断。VIII. 血清甲胎蛋白筛查在糖尿病孕妇中的重要性。
Am J Obstet Gynecol. 1982 Apr 15;142(8):1030-2.
5
[Screening of pregnant women for fetal neural tube defects by determination of the serum alpha fetoprotein level].
Ned Tijdschr Geneeskd. 1980 Jul 5;124(27):1096-101.
6
[Serum AFP determination in pregnant women].[孕妇血清甲胎蛋白测定]
Ned Tijdschr Geneeskd. 1981 Sep 12;125(37):1500-1.
7
[Determination of maternal serum alpha fetoprotein with a Polish AFP radioimmunoassay--a suitable screening method for neural tube defects?].[用波兰产甲胎蛋白放射免疫分析法测定孕妇血清甲胎蛋白——神经管缺陷的合适筛查方法?]
Zentralbl Gynakol. 1986;108(15):914-8.
8
[Quantitative acetylcholinesterase (AChE)--determination in amniotic fluid--potential for differential diagnosis in consistently high AFP levels during general AFP screening for prenatal diagnosis of open neural tube defects].[羊水乙酰胆碱酯酶(AChE)定量测定——在开放性神经管缺陷产前诊断的常规甲胎蛋白筛查中持续高甲胎蛋白水平时的鉴别诊断潜力]
Zentralbl Gynakol. 1989;111(19):1285-92.
9
Serum alpha-fetoprotein: I. Evaluation of quantitative assays adapted to automated immunoassay systems.血清甲胎蛋白:I. 适用于自动化免疫分析系统的定量检测方法的评估
Ann Clin Lab Sci. 1991 Jul-Aug;21(4):246-53.
10
Prenatal testing for maternal serum alpha-fetoprotein.
Am Fam Physician. 1987 Apr;35(4):169-74.