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颅内动脉瘤的球囊辅助弹簧圈栓塞术:发生率、并发症及血管造影结果

Balloon-assisted coil embolization of intracranial aneurysms: incidence, complications, and angiography results.

作者信息

Sluzewski Menno, van Rooij Willem Jan, Beute Guus N, Nijssen Peter C

机构信息

Department of Radiology, St. Elisabeth Ziekenhuis, Tilburg, The Netherlands.

出版信息

J Neurosurg. 2006 Sep;105(3):396-9. doi: 10.3171/jns.2006.105.3.396.

Abstract

OBJECT

The aim of this study was to assess the incidence, indications, complications, and angiography results associated with balloon-assisted coil embolization (BACE) of intracranial aneurysms and to compare these factors with those for conventional coil embolization (CE).

METHODS

Between 1995 and 2005, 827 intracranial aneurysms in 757 consecutive patients were packed with coils. Balloon-assisted coil embolization was used in 8.6% (71 of 827) of the coil insertion procedures and was more frequently used in large aneurysms, unruptured lesions, and those located on the vertebrobasilar system and carotid artery. Procedure-related complications leading to death or dependency were significantly higher in BACEs (14.1%) compared with those in CEs (3%). Packing densities and the results of 6-month follow-up angiography studies did not differ significantly between the two types of treatments. There was a strong trend for a higher retreatment rate in the aneurysms treated with BACE.

CONCLUSIONS

Balloon-assisted coil embolization of intracranial aneurysms is associated with a high complication rate and should only be used if conventional CE of these lesions is impossible or has failed and if anticipated surgical risks are too high. The BACE procedure does not improve the occlusion rates of the aneurysms on follow-up evaluation.

摘要

目的

本研究旨在评估颅内动脉瘤球囊辅助弹簧圈栓塞术(BACE)的发生率、适应证、并发症及血管造影结果,并将这些因素与传统弹簧圈栓塞术(CE)进行比较。

方法

1995年至2005年间,对757例连续患者的827个颅内动脉瘤进行了弹簧圈填塞。在827例弹簧圈置入手术中,8.6%(71例)采用了球囊辅助弹簧圈栓塞术,该方法在大型动脉瘤、未破裂病变以及位于椎基底系统和颈动脉的动脉瘤中使用更为频繁。与传统弹簧圈栓塞术(3%)相比,球囊辅助弹簧圈栓塞术导致死亡或致残的手术相关并发症显著更高(14.1%)。两种治疗方式的填塞密度及6个月随访血管造影研究结果无显著差异。接受球囊辅助弹簧圈栓塞术治疗的动脉瘤再治疗率有升高的强烈趋势。

结论

颅内动脉瘤球囊辅助弹簧圈栓塞术并发症发生率高,仅在这些病变无法进行或传统弹簧圈栓塞术失败且预期手术风险过高时使用。球囊辅助弹簧圈栓塞术在随访评估中并未提高动脉瘤的闭塞率。

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