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注意缺陷多动障碍中的执行功能

Executive functions in attention-deficit/hyperactivity disorder.

作者信息

Doyle Alysa E

机构信息

Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

出版信息

J Clin Psychiatry. 2006;67 Suppl 8:21-6.

Abstract

OBJECTIVE

To examine the association between weaknesses in executive functions and attention-deficit/hyperactivity disorder (ADHD).

METHOD

Empirical studies examining executive functions in ADHD samples were reviewed, with particular attention to results of recent meta-analyses.

RESULTS

ADHD is associated with impaired performance on measures of response inhibition, working memory, and other aspects of executive functions, yet data also suggest significant neuropsychological variability within and across ADHD samples.

CONCLUSION

ADHD may be best conceptualized as a neuropsychologically heterogeneous condition. More work is needed to characterize this heterogeneity and its clinical and pathophysiologic implications.

摘要

目的

探讨执行功能缺陷与注意力缺陷多动障碍(ADHD)之间的关联。

方法

回顾了对ADHD样本执行功能进行研究的实证性研究,尤其关注近期荟萃分析的结果。

结果

ADHD与反应抑制、工作记忆及执行功能其他方面的测量表现受损有关,但数据也表明ADHD样本内部及不同样本之间存在显著的神经心理学差异。

结论

ADHD可能最好被概念化为一种神经心理学异质性疾病。需要开展更多工作来描述这种异质性及其临床和病理生理学意义。

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