Rampichini L, De Castro Portugal F L, Severini M, Rutili D
Tumori. 1975 May-Jun;61(3):261-70. doi: 10.1177/030089167506100305.
A case of acute lymphatic leukemia in a 7-month-pregnant Italian Friesian cow, aged about 6 years and belonging to a small dairy herd of 11 cows is described. Hematologic, histopatologic and ultrastructural examinations were performed, the ultrastructural studies were confined to the lymphnodes, thymus and buffy-coat cultures from peripheral blood. The remaining animals were subjected to hematologic examination and electron microscopy examination of buffy-coat cultures from peripheral blood. C-type particles were found in phytohemagglutinin (PHA)-treated and untreated buffy-coat cultures from the leukemic cow and from the animals with persistent lymphocytosis. C-type particles were also found in milk samples from 3 cows with persistent lymphocytosis.
描述了一例急性淋巴细胞白血病病例,患牛为一头怀孕7个月的意大利弗里生奶牛,年龄约6岁,属于一个由11头奶牛组成的小型奶牛群。进行了血液学、组织病理学和超微结构检查,超微结构研究仅限于淋巴结、胸腺以及外周血的血沉棕黄层培养物。其余动物接受了血液学检查和外周血血沉棕黄层培养物的电子显微镜检查。在白血病牛和持续性淋巴细胞增多症动物经植物血凝素(PHA)处理和未处理的血沉棕黄层培养物中发现了C型颗粒。在3头持续性淋巴细胞增多症奶牛的牛奶样本中也发现了C型颗粒。