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超重和肥胖高血压成人强化生活方式治疗后的一年随访

One year follow-up of overweight and obese hypertensive adults following intensive lifestyle therapy.

作者信息

Jehn M L, Patt M R, Appel L J, Miller E R

机构信息

Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

出版信息

J Hum Nutr Diet. 2006 Oct;19(5):349-54. doi: 10.1111/j.1365-277X.2006.00711.x.

Abstract

OBJECTIVE

To examine the long-term effect on weight maintenance and dietary habits of participants in a clinical trial for weight loss.

SETTING

Community-based residents living in Maryland.

PARTICIPANTS

Forty-four hypertensive, overweight adults who participated in a randomized clinical trial of weight loss. Participants were randomized to an intensive 'lifestyle' intervention or a 'monitoring' group.

MAIN OUTCOME MEASURES

Weight, self-reported current intake of fat and fruit/fibre and self-reported barriers to maintain weight loss were assessed 1 year after the completion of the Diet, Exercise and Weight-loss Intervention Trial (DEW-IT) trial.

ANALYSIS

t-tests were used to compare groups for differences in continuous variables and chi-square tests were used to compare groups for categorical variables.

RESULTS

Fourty-two of the 44 DEW-IT subjects participated in the follow-up study. Overall, 55% (12/19) of the lifestyle intervention group remained at or below their baseline weight at 1 year, compared with 48% (11/23) of the monitoring group (P = 0.32). However, during that year, 95% (18/19) of the lifestyle intervention group and 52% (12/23) of the monitoring group gained weight from the end of the study. Both groups reported similar intake of fruits/vegetables (servings day(-1)), dietary fibre (g day(-1)) and fat (g day(-1)).

CONCLUSIONS AND IMPLICATIONS

The majority of participants who lost weight during the trial regained weight during the course of 1 year. A successful intensive 2-month programme of lifestyle modification (DEW-IT) was ineffective for long-term maintenance of weight loss.

摘要

目的

研究一项减肥临床试验参与者体重维持和饮食习惯的长期影响。

背景

居住在马里兰州的社区居民。

参与者

44名患有高血压的超重成年人,他们参与了一项减肥随机临床试验。参与者被随机分为强化“生活方式”干预组或“监测”组。

主要观察指标

在饮食、运动和减肥干预试验(DEW-IT)结束1年后,评估体重、自我报告的当前脂肪和水果/纤维摄入量以及自我报告的维持体重减轻的障碍。

分析

采用t检验比较连续变量组间差异,采用卡方检验比较分类变量组间差异。

结果

44名DEW-IT受试者中有42名参与了随访研究。总体而言,生活方式干预组中有55%(12/19)在1年后体重维持在基线水平或以下,而监测组为48%(11/23)(P = 0.32)。然而,在那一年中,生活方式干预组中有95%(18/19)和监测组中有52%(12/23)在研究结束后体重增加。两组报告的水果/蔬菜摄入量(份/天)、膳食纤维摄入量(克/天)和脂肪摄入量(克/天)相似。

结论与启示

试验期间体重减轻的大多数参与者在1年期间体重又反弹了。一项成功的为期2个月的强化生活方式改变计划(DEW-IT)对长期维持体重减轻无效。

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