White Heidi K, Cohen Harvey J
Geriatrics Division, Duke University School of Medicine, 3502 Bluezone, Box 3003, Durham, NC 27710, USA.
Med Clin North Am. 2006 Sep;90(5):967-82. doi: 10.1016/j.mcna.2006.05.017.
Providing effective and tolerable cancer treatment for the growing number of older adult patients who have cancer will require an understanding of the role of aging, comorbidity, functional status, and frailty on treatment outcomes. The incorporation of CGA into the care of older patients who have cancer will ensure that the heterogeneity of this population is considered in the development of treatment plans. It also may improve outcomes by identifying and optimally treating comorbid conditions and functional impairments. Optimal treatment of the older adult patient who has cancer starts with careful delineation of goals through conversation. The treatment plan should be comprehensive and address cancer-specific treatment, symptom-specific treatment, supportive treatment modalities, and end-of-life care.
为越来越多患癌症的老年患者提供有效且可耐受的癌症治疗,需要了解衰老、合并症、功能状态和衰弱对治疗结果的影响。将综合老年评估(CGA)纳入老年癌症患者的护理中,将确保在制定治疗计划时考虑到该人群的异质性。通过识别并优化治疗合并症和功能障碍,这也可能改善治疗结果。对老年癌症患者的最佳治疗始于通过沟通仔细确定目标。治疗计划应全面,涵盖癌症特异性治疗、症状特异性治疗、支持性治疗方式以及临终关怀。