Dentali Francesco, Crowther Mark
Department of Medicine, Insubria University, Viale Borri 57, Varese, Italy 21100.
Obstet Gynecol Clin North Am. 2006 Sep;33(3):375-88. doi: 10.1016/j.ogc.2006.05.006.
Acquired thrombophilic states are common causes of thrombosis and other forms of pregnancy-associated complications. A growing body of evidence is available to guide the use of anticoagulants in patients who have antiphospholipid antibodies; unfortunately, the results of these studies are conflicting, and solid, evidence-based treatment recommendations cannot be made. Other forms of acquired thrombophilia are uncommon or of unknown clinical significance. Treatments aimed at mitigating the impacts of these states lack clear evidence to support their use.
获得性血栓形成倾向状态是血栓形成和其他形式的妊娠相关并发症的常见原因。有越来越多的证据可用于指导抗磷脂抗体患者使用抗凝剂;不幸的是,这些研究的结果相互矛盾,无法做出可靠的、基于证据的治疗建议。其他形式的获得性血栓形成倾向并不常见或临床意义不明。旨在减轻这些状态影响的治疗方法缺乏明确的证据支持其使用。