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易栓症检测:基于证据的方法。

Testing for thrombophilia: an evidence-based approach.

作者信息

Merriman L, Greaves M

机构信息

Department of Haematology, Aberdeen Royal Infirmary, Aberdeen, UK.

出版信息

Postgrad Med J. 2006 Nov;82(973):699-704. doi: 10.1136/pgmj.2006.048090.

Abstract

Thrombophilia is a disorder of haemostasis in which there is a tendency for the occurrence of thrombosis. This tendency can be inherited or acquired. This review outlines common acquired and inherited thrombophilic conditions and discusses indications for testing. It is concluded that testing for acquired thrombophilic conditions should be considered in all cases of venous thrombosis, whereas testing for inherited thrombophilic conditions is unlikely to be helpful. If testing for inherited thrombophilia is to be carried out, the benefits, pitfalls and unwanted consequences of such testing should be taken into account.

摘要

血栓形成倾向是一种止血功能紊乱,存在血栓形成的倾向。这种倾向可以是遗传性的或后天获得的。本综述概述了常见的后天获得性和遗传性血栓形成倾向疾病,并讨论了检测的指征。结论是,对于所有静脉血栓形成病例,均应考虑检测后天获得性血栓形成倾向疾病,而检测遗传性血栓形成倾向疾病可能并无帮助。如果要进行遗传性血栓形成倾向检测,应考虑此类检测的益处、缺陷及不良后果。

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