Wang Qian, Opperman Lynne A, Havill Lorena M, Carlson David S, Dechow Paul C
Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Baylor College of Dentistry, Texas A&M University Health Science Center, Dallas, TX 75246, USA.
Anat Rec A Discov Mol Cell Evol Biol. 2006 Oct;288(10):1042-9. doi: 10.1002/ar.a.20373.
Five of the bones that characteristically comprise the cranial vault articulate on the lateral aspect of the skull at or near the cephalometric landmark referred to as the pterion. The pattern of articulation in the sutures associated with these bones varies among and within primate species and has been used as a criterion for classification in taxonomic studies, as well as in archeological and forensic studies. Within species, the sutural patterns found within the region of the pterion have remarkable consistency, which lead to the hypothesis that these patterns have a genetic basis. Sutural pattern variations were investigated at the pterion in 422 skulls from 66 rhesus monkey families with known genealogies from the long-standing colony on Cayo Santiago. Four specific types of articulation patterns were recorded. The results demonstrated that the most common suture pattern at the pterion of Cayo Santiago rhesus monkeys (86%; similar to that seen in some other anthropoid species but not humans and some apes) was characterized by an articulation between the temporal bone and parietal bone. Articulation between the sphenoid and parietal bones (type SP) accounted for 14% of the specimens and was concentrated in a dozen families. Mothers with the SP phenotype had a high incidence of offspring with SP phenotypes. Most non-SP mothers having SP offspring had siblings or family members from previous generations with the SP type. This is the first study to examine variation in sutural patterns at the pterion in pedigrees. Variation of sutural patterns shows familial aggregation, suggesting that this variation is heritable. Future work will be focused on defining the inheritance patterns of variation at the pterion, with the ultimate objective of identifying the specific genes involved and their mechanism of action.
典型构成颅顶的五块骨头在颅骨外侧与被称为翼点的头影测量标志点处或其附近相连。与这些骨头相关的缝线连接模式在灵长类物种之间以及物种内部存在差异，并已被用作分类学研究以及考古学和法医学研究中的分类标准。在一个物种内部，翼点区域发现的缝线模式具有显著的一致性，这引发了一种假设，即这些模式具有遗传基础。对来自圣地亚哥岛长期殖民地、有已知谱系的66个恒河猴家族的422个颅骨的翼点处的缝线模式变异进行了研究。记录了四种特定类型的连接模式。结果表明，圣地亚哥岛恒河猴翼点处最常见的缝线模式（86%；类似于在其他一些类人猿物种中看到的，但不同于人类和一些猿类）的特征是颞骨和顶骨之间的连接。蝶骨和顶骨之间的连接（SP型）占标本的14%，并且集中在十几个家族中。具有SP表型的母亲所生后代具有SP表型的发生率很高。大多数生出具有SP后代的非SP母亲有兄弟姐妹或上一代家庭成员具有SP类型。这是第一项研究谱系中翼点处缝线模式变异的研究。缝线模式的变异显示出家族聚集性，表明这种变异是可遗传的。未来的工作将集中于确定翼点处变异的遗传模式，最终目标是识别涉及的特定基因及其作用机制。
