Draper Bradley K, Boyd Alan S
Division of Dermatology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
J Cutan Pathol. 2006 Sep;33(9):646-8. doi: 10.1111/j.1600-0560.2006.00450.x.
Diffuse dermal angiomatosis (DDA) is an acquired, benign vascular proliferation characterized clinically by poorly circumscribed, violaceous, livedoid plaques with frequent ulceration. Histologically, a diffuse interstitial proliferation of CD31-positive endothelial cells is present within the papillary and reticular dermis. Endothelial atypia, atypical mitoses, and vasculitis are lacking. We describe a case of DDA in a 53-year-old man with peripheral vascular atherosclerosis that resolved following revascularization. Early correction of the associated ischemic peripheral vascular disease promotes resolution of this unusual clinicopathologic entity.
弥漫性皮肤血管瘤病(DDA)是一种后天性良性血管增生性疾病,临床特征为边界不清的紫蓝色、类银屑病样斑块,常伴有溃疡。组织学上,乳头层和网状真皮内可见CD31阳性内皮细胞弥漫性间质增生。缺乏内皮细胞异型性、非典型核分裂及血管炎。我们报告1例53岁男性DDA患者,其患有周围血管动脉粥样硬化,血管重建术后病情缓解。早期纠正相关的缺血性周围血管疾病可促使这种不寻常的临床病理实体消退。