Andrews Karen V, Eveson John W
Division of Oral Medicine, Pathology and Microbiology, Bristol Dental Hospital and School, Bristol, UK.
Int J Oral Maxillofac Surg. 2007 Jan;36(1):79-81. doi: 10.1016/j.ijom.2006.05.004. Epub 2006 Sep 11.
Neural invasion is a relatively common feature of squamous cell carcinomas of the head and neck and malignant salivary gland tumours. The symptoms depend on the location and the particular nerves involved, and include pain, anaesthesia, paraesthesia and cranial nerve palsy. The present case appears to be unique. A mucoepidermoid carcinoma showed evidence of neural involvement and presented with nerve stimulation inducing myokymia, rather than nerve destruction, which is the usual consequence of tumoral nerve invasion.
神经侵犯是头颈部鳞状细胞癌和恶性唾液腺肿瘤相对常见的特征。症状取决于病变位置及所累及的具体神经,包括疼痛、感觉缺失、感觉异常和脑神经麻痹。本病例似乎较为独特。一例黏液表皮样癌显示有神经受累,表现为神经刺激诱发肌束震颤,而非肿瘤侵犯神经通常导致的神经破坏。