Liu Wei, Gnepp Douglas R, de Vries Egbert, Bibawy Haidy, Solomon Marshall, Gloster Elizabeth S
Department of Pathology, SUNY Downstate Medical Center, 450, Clarkson Avenue, Brooklyn, NY 11203, USA.
Head Neck Pathol. 2009 Mar;3(1):59-62. doi: 10.1007/s12105-009-0106-5. Epub 2009 Feb 15.
Sialadenoma papilliferum is a rare tumor, primarily of minor salivary gland origin, first described by Abrams and Finck (Cancer 24:1057-63, 1969). It is both an exophytic and endophytic papillary lesion histologically resembling syringocystadenoma papilliferum of sweat gland. The tumor is considered benign although rare recurrent cases have been reported. Three cases of malignant transformation of sialadenoma papilliferum have been described in the literature. We report a high grade mucoepidermoid carcinoma arising in a background of sialadenoma papilliferum, at the base of the tongue, an unusual location for minor salivary gland neoplasms. Eleven months after excision and nodal dissection, there is no evidence of recurrence or metastasis.
乳头状涎腺瘤是一种罕见肿瘤，主要起源于小唾液腺，由艾布拉姆斯和芬克首次描述（《癌症》24:1057 - 63, 1969）。它是一种外生性和内生性乳头状病变，组织学上类似于汗腺的乳头状囊腺瘤。该肿瘤虽被认为是良性的，但已有罕见复发病例的报道。文献中已描述了3例乳头状涎腺瘤恶变的病例。我们报告1例发生于舌根乳头状涎腺瘤背景下的高级别黏液表皮样癌，这是小唾液腺肿瘤不常见的发病部位。切除及淋巴结清扫术后11个月，无复发或转移迹象。
