Espnes Ketil Arne, Spigset Olav, Delaveris Gerd Jorunn Møller, Mørland Jørg, Smith-Kielland Anne
Avdeling for klinisk farmakologi, St. Olavs Hospital, 7006 Trondheim.
Tidsskr Nor Laegeforen. 2006 Sep 7;126(17):2257-60.
There is an increasing interest in on-site testing for drugs of abuse.
Based upon our own experience and published literature, we have reviewed advantages and disadvantages of such tests. On-site testing is also evaluated in relation to the recommendations for urinary testing of drugs of abuse from the Norwegian Health Authorities.
The most significant advantage with on-site testing is provision of rapid results, usually within 5-10 minutes. Disadvantages are the risks of false positive and false negative results, the fact that numerous drugs cannot be tested for, and the limited possibilities to detect manipulation. According to Norwegian regulations, on-site testing can be used for medical purposes, but cannot be used as the only method if a positive result may cause sanctions such as e.g. exclusion from school, job dismissal or loss of parental rights. There are also special requirements for the organization of such testing.
Before starting on-site testing for drugs of abuse, it should be considered if such testing is allowed or discouraged in the specific case. It is mandatory to know how the specific test works and to have routines for follow-up of positive test results.
对滥用药物的现场检测兴趣日益浓厚。
基于我们自己的经验和已发表的文献,我们回顾了此类检测的优缺点。还根据挪威卫生当局对滥用药物尿液检测的建议对现场检测进行了评估。
现场检测最显著的优点是能快速得出结果,通常在5至10分钟内。缺点包括出现假阳性和假阴性结果的风险、许多药物无法检测以及检测作弊的可能性有限。根据挪威法规,现场检测可用于医疗目的,但如果阳性结果可能导致如被学校开除、解雇或丧失父母权利等制裁,则不能作为唯一方法使用。此类检测的组织也有特殊要求。
在开始对滥用药物进行现场检测之前,应考虑在特定情况下这种检测是允许还是不鼓励的。必须了解特定检测的工作原理,并制定阳性检测结果的后续跟进程序。