Christophersen A S, Mørland J
Statens rettstoksikologiske institutt, Oslo.
Tidsskr Nor Laegeforen. 1991 Nov 10;111(27):3300-3.
Requests are increasing for biomedical analyses of abused drugs in forensic toxicology, tests at work, testing of drug addicts during rehabilitation, and in therapeutic and other situations. Special guidelines have been prepared in forensic toxicology, with regard to the legal background, information on any sanctions in the event of positive test results, chains of custody for handling samples, analytical methods with known specificity and sensitivity, and interpretation of results based on information of legal drug use. These guidelines should also be recommended in other cases if the results might lead to negative sanctions for the individuals involved. False positive test results have been recorded from cases analysed at local laboratories which had not established the recommended guidelines. The most critical point appears to be the confirmation of positive screening results using specific methods.
在法医毒理学、工作场所检测、戒毒康复期间对吸毒者的检测以及治疗和其他情况下，对滥用药物进行生物医学分析的需求日益增加。法医毒理学已制定了特别指南，涉及法律背景、检测结果呈阳性时的任何制裁信息、样本处理的保管链、具有已知特异性和灵敏度的分析方法以及基于合法药物使用信息的结果解释。如果结果可能对相关个人导致负面制裁，在其他情况下也应推荐这些指南。当地实验室分析的一些案例记录了假阳性检测结果，这些实验室未制定推荐的指南。最关键的一点似乎是使用特定方法确认阳性筛查结果。
