Iezzi Roberto, Cotroneo Antonio Raffaele, Filippone Antonella, Di Fabio Francesca, Merlino Biagio, Bonomo Lorenzo
Department of Clinical Sciences and Bioimaging, Institute of Radiology, University G.D'annunzio, Chieti, Italy,
Abdom Imaging. 2007 Jul-Aug;32(4):489-94. doi: 10.1007/s00261-006-9136-6.
To assess the frequency and clinical impact of extravascular incidental findings on routine CT angiography of abdominal aorta or lower extremity arteries.
From January 2002 to July 2004, a total of 692 patients underwent CT angiography of abdominal aorta and lower extremity arteries. Two radiologists retrospectively reviewed by consensus cross-sectional images for the presence and clinical impact definition of extravascular findings. The revision of hospital charts, medical records, and all procedures' reports performed before and after CT angiography represented the standard of reference (SOR).
Only 373 out of 605 patients in whom extravascular findings were found had a SOR; in these patients CT angiography obtained a true-positive incidental rate of 98.9% (369/373). For the clinical impact definition of CT-angiography incidental findings, a concordance with SOR was obtained in 56.3% of patients, whereas a subsequent investigation was required in 183 patients (183/369, 49.6%). Among clinically relevant incidental findings, a total of 35 malignancies (35/894, 3.9%) were detected in 20 patients (20/423, 4.7%); in 15 patients (15/423, 3.5%) malignancy was unknown before CT-angiography exam.
A careful observation of cross-sectional images, even if "time consuming", is mandatory not only to assess vascular findings but also to avoid a misdiagnosis of clinical relevant extravascular findings.
评估腹主动脉或下肢动脉常规CT血管造影中血管外偶然发现的频率及其临床影响。
2002年1月至2004年7月,共有692例患者接受了腹主动脉和下肢动脉的CT血管造影。两名放射科医生通过共识回顾横断面图像,以确定血管外发现的存在及其临床影响定义。对CT血管造影前后的医院病历、医疗记录和所有检查报告进行复查作为参考标准(SOR)。
在发现血管外发现的605例患者中,只有373例有参考标准;在这些患者中,CT血管造影的真阳性偶然发现率为98.9%(369/373)。对于CT血管造影偶然发现的临床影响定义,56.3%的患者与参考标准一致,而183例患者(183/369,49.6%)需要进一步检查。在临床相关的偶然发现中,20例患者(20/423,4.7%)共检测到35处恶性肿瘤(35/894,3.9%);15例患者(15/423,3.5%)在CT血管造影检查前未知有恶性肿瘤。
仔细观察横断面图像,即使“耗时”,不仅对于评估血管发现是必要的,而且对于避免误诊临床相关的血管外发现也是必要的。