Hylton Penny K, Rizzi Theresa E, Allison Robin W
Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK, USA.
Vet Clin Pathol. 2006 Sep;35(3):345-7. doi: 10.1111/j.1939-165x.2006.tb00146.x.
A 1-year-old neutered male domestic shorthair cat had an ulcerated, proliferative lesion in the submandibular area that did not respond to antibiotic therapy. Impression smears from the mass revealed septic pyogranulomatous inflammation, with large numbers of pleomorphic bacteria observed intracellularly within macrophages as well as neutrophils. Bacterial culture was consistent with a diagnosis of Rhodococcus equi, a facultative intracellular coccobacillus capable of replicating within macrophages. The cat's lesion resolved after treatment with rifampin and clarithromycin. R equi should be considered as a differential diagnosis when coccobacilli are recognized within macrophages in cytologic samples.
一只1岁已绝育的雄性家养短毛猫在下颌区域有一个溃疡性、增生性病变，对抗生素治疗无反应。从肿块处采集的印片显示为化脓性脓性肉芽肿性炎症，在巨噬细胞以及中性粒细胞内可见大量多形性细菌。细菌培养结果与马红球菌的诊断一致，马红球菌是一种兼性细胞内球杆菌，能够在巨噬细胞内复制。这只猫的病变在接受利福平和克拉霉素治疗后消退。当在细胞学样本的巨噬细胞内发现球杆菌时，应将马红球菌视为鉴别诊断之一。
