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[患有酸性胃食管反流的儿童和青少年中幽门螺杆菌感染的患病率]

[Prevalence of Helicobacter pylori infection among children and youth with acid gastroesophageal reflux].

作者信息

Brazowski Jerzy, Nowak Aleksandra, Szaflarska-Popławska Anna

机构信息

Katedra i Klinika Pediatrii, Alergologii i Gastroenterologii Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy Uniwersytetu Mikołaja Kopernika w Toruniu.

出版信息

Przegl Lek. 2006;63(3):128-30.

PMID:16967700
Abstract

AIM

The aim of the study was to estimate the prevalence of Helicobacter pylori infection in patients with acid gastroesophageal reflux. PATIENTS NAD METHODS: Analysis of medical records of 160 children and youth admitted to the hospital between October 2003 and December 2004 was performed. All of these patients were diagnosed for acid gastroesophageal reflux due to clinical features and results of oesophageal pH-metry. During routine diagnostic procedures of abdominal pain, vomiting, nausea and other non-specific symptoms, endoscopy of upper gastrointestinal tract was simultaneously performed. Helicobacter pylori infection among analysed patients was diagnosed due to histopathological studies of specimens sampled during endoscopy and positive urease test.

RESULTS

Analysed group included 75 girls and 85 boys between 12 month old and 18 years old (mean age 8.47). Helicobacter pylori infection was observed in 29 patients (18.1%) of 160 analysed cases. Mean age of patients with H. pylori infection was 11.83 years, whereas mean age of patients without H. pylori infection was 7.72 years. Oesophagitis was presented in 28 (17.4%) of all patients. In the group with H. pylori infection oesophagitis was observed only in 4 patients (13,8%). In the group without H. pylori infection oesophagitis was presented in 24 patients (18,3%).

CONCLUSIONS

  1. Prevalence of Helicobacter pylori infection among patients with acid gastroesophageal reflux was lower than prevalence of infection in children and youth population of Kujawsko-Pomorski region. 2. Helicobacter pylori infection among children and youth with acid gastroesophageal reflux doesn't influence the prevalence of oesophagitis.
摘要

目的

本研究旨在评估酸性胃食管反流患者中幽门螺杆菌感染的患病率。

患者与方法

对2003年10月至2004年12月期间入院的160名儿童和青少年的病历进行分析。所有这些患者均根据临床特征和食管pH测量结果被诊断为酸性胃食管反流。在腹痛、呕吐、恶心及其他非特异性症状的常规诊断过程中,同时进行了上消化道内镜检查。通过内镜检查时采集标本的组织病理学研究及阳性尿素酶试验,诊断分析患者中的幽门螺杆菌感染情况。

结果

分析组包括75名女孩和85名男孩,年龄在12个月至18岁之间(平均年龄8.47岁)。在160例分析病例中,有29例(18.1%)观察到幽门螺杆菌感染。幽门螺杆菌感染患者的平均年龄为11.83岁,而未感染幽门螺杆菌患者的平均年龄为7.72岁。所有患者中有28例(17.4%)出现食管炎。在幽门螺杆菌感染组中,仅4例患者(13.8%)观察到食管炎。在未感染幽门螺杆菌组中,24例患者(18.3%)出现食管炎。

结论

  1. 酸性胃食管反流患者中幽门螺杆菌感染的患病率低于库亚维-波美拉尼亚地区儿童和青少年人群的感染患病率。2. 酸性胃食管反流的儿童和青少年中的幽门螺杆菌感染不影响食管炎的患病率。

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