Bidzan Leszek
Klinika Psychiatrii Rozwojowej, Zaburzeń Psychotycznych i Wieku Podeszłego Akademii Medycznej w Gdańsku.
Przegl Lek. 2006;63(3):131-3.
Vascular dementia is second most common cause of dementia. The paper highlights the most important trends in pharmacological treatment of vascular dementia. Result of a clinical trial of some agents appears to be promising. Pentoxifyline appears to be useful in multi-infarct vascular dementia. Nimodipine produced improvement in subcortical dementia. Some other agents like ginkgo biloba, acetylocholinesterase inhibitors, memantine and other also have shown mild benefit or at least were associated with some stabilization of dementia.
血管性痴呆是痴呆的第二大常见病因。本文重点介绍了血管性痴呆药物治疗的最重要趋势。一些药物的临床试验结果似乎很有前景。己酮可可碱似乎对多发性梗死性血管性痴呆有用。尼莫地平可改善皮质下痴呆。其他一些药物,如银杏叶、乙酰胆碱酯酶抑制剂、美金刚等,也显示出轻微益处,或至少与痴呆的某种稳定有关。