Rutanen E M, Pekonen F
Minerva Institute for Medical Research, Helsinki, Finland.
Acta Endocrinol (Copenh). 1990 Jul;123(1):7-13. doi: 10.1530/acta.0.1230007.
Insulin-like growth factors are important multifunctional polypeptides interacting with cell membrane receptors and soluble binding proteins. With expanding knowledge on IGF binding proteins, it is becoming evident that the IGF actions are diverse, and depend on the context set by local binding proteins. In this minireview we attempt to provide a brief summary of the recent development in this field.
胰岛素样生长因子是与细胞膜受体和可溶性结合蛋白相互作用的重要多功能多肽。随着对胰岛素样生长因子结合蛋白的了解不断深入，越来越明显的是，胰岛素样生长因子的作用多种多样，并且取决于局部结合蛋白所设定的环境。在这篇小型综述中，我们试图简要总结该领域的最新进展。
