结构生物学：药物转运的来龙去脉 - Suppr

Suppr

超能文献

Structural biology: the ins and outs of drug transport.

作者信息

Schuldiner Shimon

出版信息

Nature. 2006 Sep 14;443(7108):156-7. doi: 10.1038/443156b.

DOI:10.1038/443156b

PMID:16971936

Abstract

摘要

相似文献

Structural biology: the ins and outs of drug transport.

Nature. 2006 Sep 14;443(7108):156-7. doi: 10.1038/443156b.

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

Nature. 2006 Sep 14;443(7108):173-9. doi: 10.1038/nature05076. Epub 2006 Aug 16.

Structural biology. Flipping lipids: is the third time the charm?

Science. 2005 May 13;308(5724):963-5. doi: 10.1126/science.1113414.

[Localization of lipoproteins in Escherichia coli].

Tanpakushitsu Kakusan Koso. 2004 May;49(7 Suppl):961-4.

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

Science. 2006 Sep 1;313(5791):1295-8. doi: 10.1126/science.1131542.

Structural biology. Not just another ABC transporter.

Science. 2002 May 10;296(5570):1038-40. doi: 10.1126/science.1072484.

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism.

Science. 2002 May 10;296(5570):1091-8. doi: 10.1126/science.1071142.

A snapshot of Nature's favorite pump.

Nat Struct Biol. 2001 Nov;8(11):920-3. doi: 10.1038/nsb1101-920.

Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F.

Nat Struct Mol Biol. 2014 Dec;21(12):1097-9. doi: 10.1038/nsmb.2918. Epub 2014 Nov 17.

Crystal structure of the periplasmic component of a tripartite macrolide-specific efflux pump.

J Mol Biol. 2009 Apr 17;387(5):1286-97. doi: 10.1016/j.jmb.2009.02.048. Epub 2009 Feb 28.

引用本文的文献

The Synergistic Effect of Mud Crab Antimicrobial Peptides Sphistin and Sph With Antibiotics Azithromycin and Rifampicin Enhances Bactericidal Activity Against .

Front Cell Infect Microbiol. 2020 Oct 23;10:572849. doi: 10.3389/fcimb.2020.572849. eCollection 2020.

Expression of the AcrAB Components of the AcrAB-TolC Multidrug Efflux Pump of Yersinia enterocolitica Is Subject to Dual Regulation by OmpR.

PLoS One. 2015 Apr 20;10(4):e0124248. doi: 10.1371/journal.pone.0124248. eCollection 2015.

Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport.

Nat Cell Biol. 2014 Sep;16(9):841-51. doi: 10.1038/ncb3029. Epub 2014 Aug 31.

Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel.

J Gen Physiol. 2010 May;135(5):399-414. doi: 10.1085/jgp.201010399.

Efflux-mediated drug resistance in bacteria: an update.

Drugs. 2009 Aug 20;69(12):1555-623. doi: 10.2165/11317030-000000000-00000.

Efficacy of the combination of tachyplesin III and clarithromycin in rat models of Escherichia coli sepsis.

Antimicrob Agents Chemother. 2008 Dec;52(12):4351-5. doi: 10.1128/AAC.00086-08. Epub 2008 Sep 8.

AcrAB multidrug efflux pump regulation in Salmonella enterica serovar Typhimurium by RamA in response to environmental signals.

J Biol Chem. 2008 Aug 29;283(35):24245-53. doi: 10.1074/jbc.M804544200. Epub 2008 Jun 24.

Genomics and the mechanism of P-glycoprotein (ABCB1).

J Bioenerg Biomembr. 2007 Dec;39(5-6):481-7. doi: 10.1007/s10863-007-9115-9.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验