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Large molecular aggregates: From atmospheric aerosols to drug nanoparticles.

作者信息

Firanescu George, Hermsdorf Dana, Ueberschaer Roman, Signorell Ruth

机构信息

Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC, Canada V6T 1Z1.

出版信息

Phys Chem Chem Phys. 2006 Sep 28;8(36):4149-65. doi: 10.1039/b608433h. Epub 2006 Aug 3.

DOI:10.1039/b608433h
PMID:16971983
Abstract

Large molecular aggregates with sizes ranging from subnanometers to microns are ubiquitous. As atmospheric aerosols they influence our climate, in interstellar space they are discussed as reactive sites, and in medicine small particles are considered as promising candidates to achieve a targeted drug delivery. The present contribution is focused on the characterization of the physical-chemical properties of these particles and on their targeted generation. One of the greatest challenges is to understand the properties of these aggregates on a molecular level. The latter point is discussed in detail focussing on the vibrational dynamics of these particles.

摘要

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