Imai Kazuhiro
Department of Orthopaedic Surgery, Tokyo Metropolitan Geriatric Medical Center.
Nihon Rinsho. 2006 Sep;64(9):1621-4.
Osteoporosis is a systemic skeletal disease characterized by bone fragility and susceptibility to fracture risk. Bone fragility and fracture risk primarily reflect the integration of bone density and bone quality. Micro-computed tomography (CT) and clinical CT are useful techniques for assessing osteoporosis and predicting fracture risk. Micro-CT is useful for assessing 3D trabecular bone structure. Quantitative CT (QCT) and peripheral QCT (pQCT) are promising tools for the measurements of the bone density. CT-based finite element method (FEM) may provide some useful information about bone mechanics and predict bone strength and fracture site. The usefulness and the limitations of these techniques are reviewed in this paper.
骨质疏松症是一种全身性骨骼疾病，其特征为骨脆性增加和易发生骨折风险。骨脆性和骨折风险主要反映了骨密度和骨质量的综合情况。显微计算机断层扫描（CT）和临床CT是评估骨质疏松症和预测骨折风险的有用技术。显微CT对于评估三维小梁骨结构很有用。定量CT（QCT）和外周定量CT（pQCT）是测量骨密度的有前景的工具。基于CT的有限元方法（FEM）可能会提供一些有关骨力学的有用信息，并预测骨强度和骨折部位。本文对这些技术的实用性和局限性进行了综述。
