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德国成年代表性样本中的肥胖与精神障碍风险

Obesity and the risk for mental disorders in a representative German adult sample.

作者信息

Hach Isabel, Ruhl Uwe E, Klose Michael, Klotsche Jens, Kirch Wilhelm, Jacobi Frank

机构信息

Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Germany.

出版信息

Eur J Public Health. 2007 Jun;17(3):297-305. doi: 10.1093/eurpub/ckl227. Epub 2006 Sep 13.

DOI:10.1093/eurpub/ckl227
PMID:16973642
Abstract

BACKGROUND

A systematic approach to examining associations among obesity and socio-demographic determinants, psychological problems, and mental disorders in epidemiological samples is missing.

METHODS

Within the representative German Health Interview and Examination Survey and its Mental Health Supplement (GHS-MHS), 4181 subjects (age 18-65 years) took part in a physical examination (including measurement of body weight and height) and a standardized psychological interview (M-CIDI). Obesity (BMI > 30 kg/m(2)), somatic diseases, socio-economic variables, health-related quality of life (SF-36), and mental disorders (DSM-IV) were assessed. Data were analysed by logistic regression analyses.

RESULTS

Prevalence of obesity was 18.5%. There was a strong association between obesity and somatic conditions, as well as to low socio-economic status (SES). No psychosocial disadvantages (e.g. regarding social relationships, impairment due to mental health problems, depressed feelings) for the obese individuals were found. With the exception of a higher prevalence of anxiety disorders in obese men (12.5 versus 8.5%, OR = 1.53, CI = 1.06-2.21, disappearing when controlled for number of somatic conditions), obese persons showed no elevated rates of mental disorders.

DISCUSSION

Obesity is associated with a low SES and some somatic disadvantages but not with other social or emotional disadvantages that have been often assumed to be very prevalent in that group. From the population-based perspective, obesity per se seems not to be associated with a higher risk for suffering from mental disorders, whereas relations between specific aspects of obesity and specific types of psychopathology still need further study.

摘要

背景

在流行病学样本中,缺乏一种系统的方法来研究肥胖与社会人口学决定因素、心理问题和精神障碍之间的关联。

方法

在具有代表性的德国健康访谈与检查调查及其心理健康补充调查(GHS-MHS)中,4181名受试者(年龄在18 - 65岁之间)参加了体格检查(包括体重和身高测量)以及标准化心理访谈(M-CIDI)。评估了肥胖(BMI > 30 kg/m²)、躯体疾病、社会经济变量、健康相关生活质量(SF-36)和精神障碍(DSM-IV)。通过逻辑回归分析对数据进行分析。

结果

肥胖患病率为18.5%。肥胖与躯体状况以及低社会经济地位(SES)之间存在密切关联。未发现肥胖个体存在心理社会劣势(例如在社会关系、因心理健康问题导致的损害、抑郁情绪方面)。除了肥胖男性中焦虑障碍患病率较高(12.5%对8.5%,OR = 1.53,CI = 1.06 - 2.21,在控制躯体疾病数量后消失)外,肥胖者的精神障碍发生率并未升高。

讨论

肥胖与低社会经济地位和一些躯体劣势相关,但与通常认为在该群体中非常普遍的其他社会或情感劣势无关。从基于人群的角度来看,肥胖本身似乎与患精神障碍的较高风险无关,而肥胖的特定方面与特定类型精神病理学之间的关系仍需进一步研究。

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