Igarashi M, Weber S C, Alford B R, Coats A C, Jerger J
Arch Otolaryngol. 1975 Sep;101(9):577-83. doi: 10.1001/archotol.1975.00780380055015.
A 19-year-old woman with cryptococcal meningitis died as a result of her disease, in spite of both intravenous and intraventricular administration of amphotericin B. Gross and microscopic examinations revealed multiple cysts containing Cryptococcus neoformans within the central nervous system. Studies of the temporal bones revealed both neural and end organ destruction with the presence of Cryptococcus when stained by Gomori methenamine silver nitrate method. We present the results of audiometric and vestibular examinations. The case history depicts a progressive neurological involvement by Cryptococcus.
一名19岁患有隐球菌性脑膜炎的女性尽管接受了静脉和脑室内注射两性霉素B治疗，但仍因该病死亡。大体和显微镜检查显示中枢神经系统内有多个含有新型隐球菌的囊肿。颞骨研究显示，用Gomori硝酸银染色时，存在隐球菌的情况下神经和终末器官均有破坏。我们展示了听力测定和前庭检查的结果。病例史描述了隐球菌引起的进行性神经受累情况。
