一名艾滋病患者发生喷他脒诱发的急性胰腺炎。

Pentamidine-induced acute pancreatitis in a patient with AIDS.

作者信息

Pauwels A, Eliaszewicz M, Larrey D, Lacassin F, Poirier J M, Meyohas M C, Frottier J

机构信息

Department of Infectious Diseases, Hôpital Saint-Antoine, Paris, France.

出版信息

J Clin Gastroenterol. 1990 Aug;12(4):457-9. doi: 10.1097/00004836-199008000-00022.

DOI:10.1097/00004836-199008000-00022

PMID:1697871

Abstract

We report pentamidine-induced acute pancreatitis in a patient with the acquired immunodeficiency syndrome (AIDS). The course of this pancreatitis was prolonged but favorable. Pentamidine was detected in serum as late as one month after discontinuation of therapy. The special pharmacokinetics of this drug may account for the potential severity of pentamidine-induced acute pancreatitis.

摘要

我们报告了1例获得性免疫缺陷综合征（AIDS）患者发生喷他脒诱发的急性胰腺炎。该胰腺炎病程延长，但预后良好。在停药后1个月血清中仍可检测到喷他脒。该药特殊的药代动力学可能是喷他脒诱发急性胰腺炎潜在严重性的原因。