Temml Christian, Wehrberger Clemens, Riedl Claus, Ponholzer Anton, Marszalek Martin, Madersbacher Stephan
Department of Preventive Health, City of Vienna, Austria.
Eur Urol. 2007 Mar;51(3):803-8; discussion 809. doi: 10.1016/j.eururo.2006.08.028. Epub 2006 Aug 30.
To determine the prevalence of interstitial cystitis (IC) symptoms in an urban female population, to study their impact on quality of life and sexual function, and to identify correlates for IC symptoms.
Women attending a voluntary health survey project in Vienna underwent a detailed health investigation and completed a questionnaire containing the O'Leary-Sant IC questionnaire. Women with high (> or =12) symptom and problem scores including nocturia (>2) and pain were considered most likely to have IC.
A total of 981 women, aged 19 to 89 yr (mean, 49.1+/-14.7 yr), participated in the study. Of these, 57.9% had a low IC symptom score (score 0-3), 25.9% mild IC symptoms (score 4-6), 13.9% moderate symptoms (score 7-11), and 2.3% a high symptom score (score 12-20). The IC problem score revealed a similar pattern. The overall prevalence of IC was 306/100,000 women with the highest value (464/100,000) in middle-aged women (40-59 yr). About two thirds of the women with moderate to high risk for IC reported an impairment of quality of life; 35% reported an effect on their sexual life. In a multivariate analysis, bowel disorders (p=0.016) and psychological stress (p=0.029) were correlated to the probability of IC.
The prevalence of IC symptoms is higher than previously estimated and substantially affects quality of life and sexuality.
确定城市女性人群中间质性膀胱炎（IC）症状的患病率，研究其对生活质量和性功能的影响，并找出与IC症状相关的因素。
参加维也纳一项自愿健康调查项目的女性接受了详细的健康调查，并完成了一份包含奥利里 - 桑特IC问卷的调查问卷。症状和问题得分高（≥12分），包括夜尿症（>2次）和疼痛的女性被认为最有可能患有IC。
共有981名年龄在19至89岁（平均49.1±14.7岁）的女性参与了该研究。其中，57.9%的女性IC症状得分低（0 - 3分），25.9%有轻度IC症状（4 - 6分），13.9%有中度症状（7 - 11分），2.3%症状得分高（12 - 20分）。IC问题得分呈现相似模式。IC的总体患病率为306/100,000名女性，中年女性（40 - 59岁）患病率最高（464/100,000）。约三分之二有中度至高度IC风险的女性报告生活质量受损；35%报告对其性生活有影响。在多变量分析中，肠道疾病（p = 0.016）和心理压力（p = 0.029）与患IC的可能性相关。
IC症状的患病率高于先前估计，且对生活质量和性功能有重大影响。
