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使用针状内镜器械行腹腔镜下醛固酮瘤肾上腺部分切除术。

Laparoscopic partial adrenalectomy for aldosterone-producing adenomas with needlescopic instruments.

作者信息

Liao Chun-Hou, Chueh Shih-Chieh, Wu Kwan-Dun, Hsieh Ming-Hsueh, Chen Jun

机构信息

Department of Urology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

出版信息

Urology. 2006 Sep;68(3):663-7. doi: 10.1016/j.urology.2006.04.036. Epub 2006 Sep 18.

Abstract

INTRODUCTION

Laparoscopic total adrenalectomy is the treatment of choice for aldosterone-producing adenomas (APAs). There have not been many reports of laparoscopic partial adrenalectomy, although this procedure offers benefits to patients with suspected bilateral APAs or an APA in a solitary adrenal gland. We describe the feasibility of a novel technique of laparoscopic partial adrenalectomy for APA solely using 2-mm working instruments and a 5 to 10-mm telescope.

TECHNICAL CONSIDERATIONS

Six unilateral and two bilateral partial adrenalectomies were performed laparoscopically. Only one umbilical 12-mm port for the telescope and two (for left adenomas) or three (for right adenomas) subcostal 2-mm working ports were used. Hemostasis and transection of adrenal tissues were performed using a 2-mm mini-bipolar coagulator and 2-mm scissors.

RESULTS

All laparoscopic operations were successfully performed using only 2-mm working instruments and a 5 or 10-mm 30 degree telescope with no intraoperative or postoperative complications. Blood loss was minimal, and the operative times were comparable to those of previous reports. All patients had low pain scores, required minimal amounts of narcotics postoperatively, and reported excellent cosmetic results for the wounds. The pathologic examinations confirmed complete excision of all adenomas with intact capsules. The plasma aldosterone concentrations and renin activities returned to normal ranges postoperatively in all patients. At a mean follow-up of 25 months (range 13 to 48), 7 (87.5%) were cured of their hypertension and 1 had the hypertensive medications significantly reduced.

CONCLUSIONS

Laparoscopic partial adrenalectomy for APAs using 2-mm working instruments and a 5 to 10-mm telescope is a safe and effective treatment alternative.

摘要

引言

腹腔镜下全肾上腺切除术是治疗醛固酮瘤(APA)的首选方法。尽管腹腔镜部分肾上腺切除术对疑似双侧APA或单肾上腺APA患者有益,但相关报道并不多。我们描述了一种仅使用2毫米工作器械和5至10毫米腹腔镜的腹腔镜下部分肾上腺切除术新技术的可行性。

技术要点

腹腔镜下进行了6例单侧和2例双侧部分肾上腺切除术。仅使用一个用于腹腔镜的脐部12毫米端口和两个(用于左侧腺瘤)或三个(用于右侧腺瘤)肋下2毫米工作端口。使用2毫米微型双极电凝器和2毫米剪刀进行肾上腺组织的止血和切断。

结果

所有腹腔镜手术均仅使用2毫米工作器械和5或10毫米30度腹腔镜成功完成,无术中或术后并发症。失血极少,手术时间与既往报道相当。所有患者疼痛评分低,术后所需麻醉药量极少,且伤口美容效果极佳。病理检查证实所有腺瘤均完整包膜完整切除。所有患者术后血浆醛固酮浓度和肾素活性均恢复至正常范围。平均随访25个月(范围13至48个月),7例(87.5%)高血压治愈,1例高血压药物用量显著减少。

结论

使用2毫米工作器械和5至10毫米腹腔镜进行腹腔镜下APA部分肾上腺切除术是一种安全有效的治疗选择。

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