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[脊髓和马尾的慢性纤维增生性软脑膜炎]

[Chronic fibroplastic leptomeningitis of the spinal cord and cauda equina].

作者信息

Benini A, Blanco J

机构信息

Neurochirurgische Klinik, Kantonsspital, St. Gallen.

出版信息

Schweiz Arch Neurol Psychiatr (1985). 1990;141(4):293-343.

PMID:1697979
Abstract

Chronic (seldom subacute) low-grade spinal leptomeningitis, cystic and adhesive in natura, is a clinicopathologic condition known by several names in medical literature (arachnoiditis, arachnoditis adhesiva circumscripta, a.s.o.). The cystic structures are not cysts in the true sense of the word. They are in reality collections of cerebrospinal fluid walled off by meningeal adhesions. The extent of the leptomeningitis varies from a well-localized lesion to a diffused process involving the entire cereprospinal axis. In some cases the chronic proliferative changes lead to calcification and ossification of the leptomeninx. As well the circumscribed adhesive as the cystic form can produce a spinal cord compression syndrome similar to a tumor or a hydro-syringomyelia. Progressive paraparesis with difficulties of bladder and bowel function may nevertheless be arrested, or spontaneous remission may occur, perhaps due to temporary improvement of the local circulation of spinal fluid. An almost typical sciatic syndrome can be occasionally associated with a thickening of the leptomeninx and cystic spinal fluid collection in the region of the cauda equina. The lumbar adhesive and cystic form is as a rule a more benign disease then leptomeningitis occurring at thoracic or cervical levels. The etiological factors are trauma, spinal anesthesia, myelography, blood in the subarachnoid space, previous operations and infections. When the origin of the illness remains unidentified, low grade bacterial or viral infections can be presumed. We operated 2 patients with circumscribed severe leptomeningitis several segments far away from an intradural meningeoma. Such illness is uncommon, but not very rare. From 1970 until the end of 1986 we have carried out 33 laminectomies on 26 patients because of spinal leptomeningitis among 603 patients operated because of spinal cord compression (4.31%). Our cases are presented and literature is discussed. The dilemma what we have to do with a patient with symptomatic spinal leptomeningitis is open: the microsurgery can help the patient significantly, even if complete recovery is rare. In view of the extreme variety of these lesions a circumspect, sometime skeptical analysis of each patient must precede decision about surgery. We try to give some indications for microsurgery.

摘要

慢性(很少为亚急性)低度脊髓软脊膜炎,本质上为囊性和粘连性,是一种在医学文献中有多个名称的临床病理状况(蛛网膜炎、局限性粘连性蛛网膜炎等)。这些囊性结构并非真正意义上的囊肿。实际上,它们是由脑膜粘连分隔开的脑脊液聚集物。软脊膜炎的范围从局限性病变到累及整个脑脊髓轴的弥漫性病变不等。在某些情况下,慢性增殖性改变会导致软脑膜钙化和骨化。局限性粘连型和囊肿型均可产生类似于肿瘤或脊髓空洞症的脊髓压迫综合征。然而,伴有膀胱和肠道功能障碍的进行性截瘫可能会停止,或者可能会出现自发缓解,这可能是由于脊髓液局部循环的暂时改善。几乎典型的坐骨神经综合征偶尔可与马尾区域软脑膜增厚和脊髓液囊肿形成相关。腰椎粘连型和囊肿型通常比发生在胸段或颈段的软脊膜炎病情更良性。病因包括创伤、脊髓麻醉、脊髓造影、蛛网膜下腔出血、既往手术和感染。当疾病的起源不明时,可推测为低度细菌或病毒感染。我们为2例患有局限性严重软脊膜炎且距硬脊膜内脑膜瘤数节段远的患者进行了手术。这种疾病并不常见,但也并非极为罕见。从1970年到1986年底,在因脊髓压迫而接受手术的603例患者中,我们因脊髓软脊膜炎为26例患者进行了33次椎板切除术(4.31%)。我们展示了病例并讨论了相关文献。对于有症状的脊髓软脊膜炎患者该如何处理的困境仍然存在:显微手术可显著帮助患者,即便完全恢复很少见。鉴于这些病变的极端多样性,在决定手术之前必须对每位患者进行谨慎、有时甚至是怀疑性的分析。我们试图给出一些显微手术的指征。

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