A cerebrospinal fluid study of the pathophysiology of panic disorder associated with alcoholism.
作者信息
George D T, Adinoff B, Ravitz B, Nutt D J, De Jong J, Berrettini W, Mefford I N, Costa E, Linnoila M
机构信息
Laboratory of Clinical Studies National Institute on Alcohol Abuse and Alcoholism, National Institute of Mental Health, Bethesda, Maryland 20892.
出版信息
Acta Psychiatr Scand. 1990 Jul;82(1):1-7. doi: 10.1111/j.1600-0447.1990.tb01345.x.
In order to investigate the neurochemistry of panic disorder in alcoholics, we measured various cerebrospinal fluid (CSF) parameters in subjects with both conditions and compared them with an age- and sex-matched population of alcoholics and normal controls. When height, age and weight were covaried, subjects with panic disorder had higher levels of B-endorphin in CSF. There were no differences in other CSF measures between the groups. Alcoholics with panic disorder had higher plasma MHPG concentrations compared with alcoholics without panic disorder but these were not statistically different from controls.
Zotero 插件