Carmalt H L, Gillett D J, Hollinshead J W
Department of Surgery, Repatriation General Hospital, Concord, New South Wales.
Aust N Z J Surg. 1990 Oct;60(10):759-63. doi: 10.1111/j.1445-2197.1990.tb07470.x.
Five hundred and eleven patients with adenocarcinoma of the stomach were reviewed. Weight loss and abdominal pain were the most common symptoms. One-third of patients were found to have proximal gastric lesions with dysphagia being a major symptom in 23% of all patients. Laparotomy was performed on 88% of patients with 56% of the entire series undergoing gastric resection. The overall 5-year survival rate was 12.3% and for curative resection 43%. The 5-year survival rate of patients undergoing total gastrectomy was 53% and for patients undergoing subtotal or partial gastrectomy the 5-year survival rate was 42%. The operative mortality, similar in both groups, was 8.1% versus 5.6%. Palliation was better achieved by resection than bypass. Total gastrectomy for palliation was undertaken in 48 patients. This group of patients has achieved a good quality of life and a mean survival rate of 12.5 months.
对511例胃腺癌患者进行了回顾性研究。体重减轻和腹痛是最常见的症状。三分之一的患者被发现有近端胃部病变，吞咽困难是所有患者中23%的主要症状。88%的患者接受了剖腹手术，整个系列中有56%的患者接受了胃切除术。总体5年生存率为12.3%，根治性切除术后为43%。接受全胃切除术患者的5年生存率为53%，接受次全或部分胃切除术患者的5年生存率为42%。两组的手术死亡率相似，分别为8.1%和5.6%。切除比旁路手术能更好地实现姑息治疗。48例患者接受了姑息性全胃切除术。这组患者获得了良好的生活质量，平均生存率为12.5个月。
