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血清视黄醇结合蛋白的共同表位:一项单克隆抗体研究

Common epitopes of serum retinol-binding proteins: a study with monoclonal antibodies.

作者信息

Reddy K, Karande A A, Adiga P R

机构信息

Department of Biochemistry, Indian Institute of Science, Bangalore.

出版信息

Biochem Int. 1990;21(2):367-76.

PMID:1698367
Abstract

Monoclonal antibodies were raised against purified chicken retinol-binding protein. These were characterised extensively with respect to their ability to recognize retinol-binding proteins from different species. The monoclonal antibodies exhibited differential recognition characteristics. Though the majority presented restricted reactivities, one out of the four monoclonal antibodies studied cross-reacted with retinol-binding proteins from all species tested so far.

摘要

制备了针对纯化鸡视黄醇结合蛋白的单克隆抗体。对这些抗体识别不同物种视黄醇结合蛋白的能力进行了广泛表征。这些单克隆抗体表现出不同的识别特性。虽然大多数抗体呈现出有限的反应性,但在所研究的四种单克隆抗体中,有一种与迄今为止测试的所有物种的视黄醇结合蛋白发生交叉反应。

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