Larsen Torben, Olsen Tom S, Sorensen Jan
Centre for Applied Health Services Research and Technology Assessment, University of Southern Denmark, Odense C.
Int J Technol Assess Health Care. 2006 Summer;22(3):313-20. doi: 10.1017/s0266462306051208.
A comprehensive and systematic assessment (HTA) of early home-supported discharge by a multidisciplinary team that plans, coordinates, and delivers care at home (EHSD) was undertaken and the results were compared with that of conventional rehabilitation at stroke units.
A systematic literature search for randomized trials (RCTs) on "early supported discharge" was closed in April 2005. RCTs on EHSD without information on (i) death or institution at follow-up, (ii) change in Barthél Index, (iii) length of hospital stay, (iv) intensity of home rehabilitation, or (v) baseline data are excluded. Seven RCTs on EHSD with 1,108 patients followed 3-12 months after discharge are selected for statistical meta-analysis of outcomes. The costs are calculated as a function of the average number of home training sessions. Economic evaluation is organized as a test of dominance (both better outcomes and lower costs).
The odds ratio (OR) for "Death or institution" is reduced significantly by EHSD: OR = .75 (confidence interval [CI], .46-.95), and number needed to treat (NNT) = 14. Referrals to institution have OR = .45 (CI, .31-.96) and NNT = 20. The reduction of the rate of death is not significant. Length of stay is significantly reduced by 10 days (CI, 2.6-18 days). All outcomes have a nonsignificant positive covariance. The median number of home sessions is eleven, and the average cost per EHSD is 1,340 USD. The "action mechanism" and financial barriers to EHSD are discussed.
EHSD is evidenced as a dominant health intervention. However, financial barriers between municipalities and health authorities have to be overcome. For qualitative reasons, a learning path of implementation is recommended where one stroke unit in a region initiates EHSD for dissemination of new experience to the other stroke units.
对由多学科团队进行的早期家庭支持出院(EHSD)进行全面系统的卫生技术评估(HTA),该团队负责在家中规划、协调和提供护理,并将结果与卒中单元的传统康复结果进行比较。
2005年4月结束了对“早期支持出院”随机试验(RCT)的系统文献检索。排除了关于EHSD但没有以下信息的RCT:(i)随访时的死亡或住院情况;(ii)巴氏指数的变化;(iii)住院时间;(iv)家庭康复强度;或(v)基线数据。选择7项关于EHSD的RCT,共1108例患者,在出院后3至12个月进行随访,对结果进行统计荟萃分析。成本根据家庭训练课程的平均数量计算。经济评估作为优势性检验进行组织(结果更好且成本更低)。
EHSD显著降低了“死亡或住院”的比值比(OR):OR = 0.75(置信区间[CI],0.46 - 0.95),需治疗人数(NNT) = 14。住院转诊的OR = 0.45(CI,0.31 - 0.96),NNT = 20。死亡率的降低不显著。住院时间显著缩短10天(CI,2.6 - 18天)。所有结果均有不显著的正协方差。家庭训练课程的中位数为11次,每次EHSD的平均成本为1340美元。讨论了EHSD的“作用机制”和经济障碍。
EHSD被证明是一种优势性的健康干预措施。然而,必须克服市政当局和卫生当局之间的经济障碍。出于质量原因,建议采用一种实施学习路径,即一个地区的一个卒中单元启动EHSD,以便向其他卒中单元传播新经验。