Cademartiri Filippo, Mollet Nico R, Lemos Pedro A, Saia Fransesco, Midiri Massimo, de Feyter Pim J, Krestin Gabriel P
Department of Radiology, Erasmus Medical Center, Dr. Molewaterplein 40, Rotterdam, The Netherlands.
AJR Am J Roentgenol. 2006 Oct;187(4):W430-3. doi: 10.2214/AJR.05.1406.
The purpose of this study was to investigate whether the amount of intracoronary attenuation influences the diagnostic accuracy of MDCT coronary angiography in the detection of clinically significant stenosis.
One hundred twenty patients in sinus rhythm with suspected coronary artery disease who underwent MDCT of the heart and conventional coronary angiography were retrospectively selected. The population was divided into two groups depending on median (326 H) coronary vascular enhancement (i.e., low attenuation and high attenuation). The diagnostic accuracy of MDCT for the detection of clinically significant coronary artery lesions (> or = 50% lumen reduction) in both groups was compared with that of quantitative coronary angiography.
The sensitivity of MDCT was 90% and 93% for the low- and high-attenuation groups, respectively. The specificity was 95% and 97%.
Greater intracoronary attenuation leads to higher diagnostic accuracy in the detection of coronary artery stenosis with MDCT.
本研究旨在探讨冠状动脉内衰减量是否会影响多层螺旋CT(MDCT)冠状动脉造影检测临床显著狭窄的诊断准确性。
回顾性选取120例窦性心律且疑似冠心病并接受心脏MDCT及传统冠状动脉造影的患者。根据冠状动脉血管强化的中位数(326 H)将人群分为两组(即低衰减组和高衰减组)。将两组中MDCT检测临床显著冠状动脉病变(管腔狭窄≥50%)的诊断准确性与定量冠状动脉造影的诊断准确性进行比较。
低衰减组和高衰减组中MDCT的敏感性分别为90%和93%。特异性分别为95%和97%。
冠状动脉内衰减越大,MDCT检测冠状动脉狭窄的诊断准确性越高。