Zerbino D D, Solomenchuk T N
Arkh Patol. 2006 Jul-Aug;68(4):49-54.
The term "atherosclerosis" is erroneously used for the definition of different types of arteriosclerosis, each of them has not only its characteristic structural signs, but also its specific causes and the mechanisms of its development. Particularly, young subjects are observed to mainly have lipid-free arterial intimal lesion with formed myofibrous, fibrous hyalinized plaques, and circular or focal myoelastic intimal hyperplasia. This type of atherosclerosis more commonly occurs in those who are occupationally exposed to xenobiotics. The establishment of the actual cause of each type of arteriosclerosis will open up fresh opportunities for the prevention of the diseases that are responsible for high morbidity and disability rates in the past decades.
术语“动脉粥样硬化”被错误地用于定义不同类型的动脉硬化，每一种动脉硬化不仅有其特征性的结构体征，还有其特定的病因及其发展机制。特别是，观察到年轻受试者主要有无脂质的动脉内膜病变，伴有形成的肌纤维、纤维玻璃样变斑块，以及圆形或局灶性肌弹性内膜增生。这种类型的动脉粥样硬化更常见于职业性接触外源性物质的人群。确定每种类型动脉硬化的实际病因将为预防过去几十年来导致高发病率和高致残率的疾病带来新的机遇。
