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1
A new method for monitoring subclinical virus infections of the central nervous system in mice.一种监测小鼠中枢神经系统亚临床病毒感染的新方法。
Br J Exp Pathol. 1975 Aug;56(4):287-90.
2
Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation.塞姆利基森林病毒诱导的免疫介导性脱髓鞘：辐射的影响
Br J Exp Pathol. 1987 Feb;68(1):101-13.
3
Long-term effects of Semliki Forest virus infection in the mouse central nervous system.
Neuropathol Appl Neurobiol. 1997 Jun;23(3):235-41.
4
The effect of gold sodium thiomalate and its constituent part, thiomalate, on the virus titres and the lysosomal enzyme activity in peritoneal macrophages of Swiss/A2G mice infected with the avirulent strain of Semliki Forest virus.硫代苹果酸金钠及其组成部分硫代苹果酸对感染了无毒力塞姆利基森林病毒株的瑞士/A2G小鼠腹腔巨噬细胞中病毒滴度和溶酶体酶活性的影响。
J Exp Pathol (Oxford). 1990 Jun;71(3):359-66.
5
Virus tropism, distribution, persistence and pathology in the corpus callosum of the Semliki Forest virus-infected mouse brain: a novel system to study virus-oligodendrocyte interactions.塞姆利基森林病毒感染小鼠大脑胼胝体中的病毒嗜性、分布、持久性及病理学：一种研究病毒与少突胶质细胞相互作用的新系统
Neuropathol Appl Neurobiol. 2006 Aug;32(4):397-409. doi: 10.1111/j.1365-2990.2006.00739.x.
6
Pathogenesis of Semliki Forest virus encephalitis.Semliki森林病毒脑炎的发病机制。
J Neurovirol. 2002 Dec;8 Suppl 2:66-74. doi: 10.1080/135502802901068000.
7
The significance of the 3'-nontranslated region and E2 amino acid mutations in the virulence of Semliki Forest virus in mice.塞姆利基森林病毒3'非翻译区和E2氨基酸突变对其在小鼠中致病性的意义
Virology. 1998 Mar 30;243(1):66-77. doi: 10.1006/viro.1998.9031.
8
Further studies of macrophages in relationship to avirulent Semliki Forest virus infections.关于无毒力的Semliki森林病毒感染与巨噬细胞关系的进一步研究。
Br J Exp Pathol. 1980 Apr;61(2):150-5.
9
Predisposition to EAE induction in resistant mice by prior infection with Semliki Forest virus.
J Immunol. 1987 May 15;138(10):3264-8.
10
Replication of the A7(74) strain of Semliki Forest virus is restricted in neurons.
Virology. 1993 Aug;195(2):627-37. doi: 10.1006/viro.1993.1414.

引用本文的文献

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Inapparent Tick-Borne Orthoflavivirus Infection in : A Model for Antiviral Drug and Vaccine Research.隐匿性蜱传正黄病毒感染：抗病毒药物和疫苗研究的模型
Vaccines (Basel). 2023 Nov 25;11(12):1754. doi: 10.3390/vaccines11121754.
2
The relationship between axonal transport of protein and demyelination in the optic nerves of mice infected with Semliki Forest virus.感染Semliki森林病毒的小鼠视神经中蛋白质轴突运输与脱髓鞘之间的关系。
Brain Res. 1986 Nov 5;397(1):9-15. doi: 10.1016/0006-8993(86)91364-8.
3
Motor activity changes in scrapie-affected mice.感染羊瘙痒病小鼠的运动活动变化
Br J Exp Pathol. 1976 Dec;57(6):742-6.

本文引用的文献

1
The course of Semliki Forest virus infection in mice.小鼠感染Semliki森林病毒的病程。
Br J Exp Pathol. 1967 Aug;48(4):395-402.
2
Behaviour in emergence and open-field tests of normal and scrapie mice.正常小鼠和羊瘙痒症小鼠在旷场试验及新环境探索试验中的行为表现
Res Vet Sci. 1968 Nov;9(6):600-1.
3
An investigation of a new instrument to measure motor activity of small animals.
Psychopharmacologia. 1969;14(2):157-63. doi: 10.1007/BF00403689.
4
Infection patterns in mice of an avirulent and virulent strain of Semliki Forest virus.减毒和强毒株塞姆利基森林病毒在小鼠中的感染模式
Br J Exp Pathol. 1971 Dec;52(6):669-77.
5
The virulence of original and derived strains of Semliki forest virus for mice, guinea-pigs and rabbits.塞姆利基森林病毒原始株及衍生株对小鼠、豚鼠和兔子的毒力。
J Gen Virol. 1971 Aug;12(2):141-60. doi: 10.1099/0022-1317-12-2-141.
6
Encephalopathy in mice following inapparent Semliki Forest Virus (S.F.V.) infection.隐性感染Semliki森林病毒（S.F.V.）后小鼠的脑病
Br J Exp Pathol. 1972 Apr;53(2):125-9.
7
Changes in drinking and feeding habits of mice with experimental scrapie.患有实验性羊瘙痒病小鼠的饮水和进食习惯变化
J Comp Pathol. 1972 Oct;82(4):415-27. doi: 10.1016/0021-9975(72)90041-2.

一种监测小鼠中枢神经系统亚临床病毒感染的新方法。

A new method for monitoring subclinical virus infections of the central nervous system in mice.

作者信息

Suckling A J, Bateman S, Webb H E

出版信息

Br J Exp Pathol. 1975 Aug;56(4):287-90.

PMID:169870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2072771/
Abstract

The course of a subclinical virus infection of the central nervous system (CNS) of mice has been followed by measuring spontaneous motor activity using Animex equipment. A significant drop in activity occurred on the 5th and 6th day after inoculation with the A774 (avirulent) strain of Semliki Forest virus (SFV) before histological changes were apparent but at the same time as maximum brain virus titre. The relationship of the fall in activity to changes in the pattern of weight gain, food and water intake was also investigated.

摘要

通过使用Animex设备测量自发运动活动，对小鼠中枢神经系统（CNS）亚临床病毒感染的病程进行了跟踪。在用Semliki森林病毒（SFV）的A774（无毒）株接种后的第5天和第6天，活动出现显著下降，此时组织学变化尚不明显，但与脑病毒滴度最高时同步。还研究了活动下降与体重增加模式、食物和水摄入量变化之间的关系。