Rudling R, Hassan A B, Kitau J, Mandir N, Goodlad R A
BSU Unit, Cancer Research UK, London Research Institute, London, UK.
Cell Prolif. 2006 Oct;39(5):415-20. doi: 10.1111/j.1365-2184.2006.00391.x.
Many mouse models of neoplasia and pre-neoplasia require the examination of whole mounts of the gastrointestinal tract. A simple device has been produced to facilitate the rapid preparation of mouse intestines for subsequent quantification of tumours and pre-neoplastic lesions such as aberrant crypt foci. The device greatly speeds up the production of whole mounts and also provides far more consistent and better-quality preparations.
许多肿瘤形成和肿瘤前期的小鼠模型需要对胃肠道进行整体标本检查。已制作出一种简单装置,以方便快速制备小鼠肠道,用于后续对肿瘤和肿瘤前病变(如异常隐窝灶)进行定量分析。该装置大大加快了整体标本的制作速度,还能提供更加一致且质量更高的标本。