De Simone Roberto, Daquin Géraldine, Genton Pierre
Department of Neurology, S. Eugenio Hospital, Rome, Italy.
Epileptic Disord. 2006 Sep;8(3):223-7.
Myoclonic epilepsy is being increasingly recognized as a late-onset complication in middle-aged or elderly patients with Down syndrome, in association with cognitive decline. We show video and EEG recordings of two patients, both aged 56 years, diagnosed with this condition. At onset, myoclonic epilepsy in elderly DS patients may resemble, in its clinical expression, the classical juvenile myoclonic epilepsy with the characteristic occurrence of jerks on awakening. It is clearly associated with an Alzheimer-type dementia, and may also occur in non-DS patients with Alzheimer's disease: hence the possible denomination of "senile myoclonic epilepsy". [Published with video sequences].
肌阵挛性癫痫正越来越多地被视为中年或老年唐氏综合征患者的迟发性并发症，并伴有认知能力下降。我们展示了两名均为56岁、被诊断患有此病的患者的视频和脑电图记录。在发病时，老年唐氏综合征患者的肌阵挛性癫痫在临床表现上可能类似于典型的青少年肌阵挛性癫痫，其特征是在醒来时出现抽搐。它显然与阿尔茨海默型痴呆有关，也可能发生在患有阿尔茨海默病的非唐氏综合征患者中：因此可能被称为“老年性肌阵挛性癫痫”。[随视频序列发表]
