Polletto Travis J, Ngo Anthony K, Tchapyjnikov Alexei, Levin Ken, Tran Danh, Fried Nathaniel M
Department of Urology, Johns Hopkins University, Baltimore, Maryland 21224, USA.
Lasers Surg Med. 2006 Sep;38(8):787-91. doi: 10.1002/lsm.20382.
Endoscopic applications of the Erbium:YAG laser have been limited due to the lack of a suitable optical fiber delivery system. The purpose of this study was to compare the transmission of Er:YAG laser radiation through germanium oxide trunk fibers with silica and sapphire fiber tips for potential use in contact tissue ablation during endoscopy.
STUDY DESIGN/MATERIALS AND METHODS: Er:YAG laser radiation with a wavelength of 2.94 microm, pulse length of 300 microseconds, pulse energies from 5 to 1,360 mJ, coupled into pulse repetition rates of 3-10 Hz, was through 1-m-long germanium oxide fibers with either 1-cm-long, 550-microm-diameter silica or sapphire tips.
Transmission through the germanium oxide/sapphire fibers measured 65+/-5% compared with 55+/-4% for the germanium oxide/silica fibers (P<0.05). The damage threshold for the hybrid fibers averaged 309+/- 44 mJ and 126+/-43 mJ, respectively (n = 7 fibers each) (P<0.05). The highest pulse energies transmitted through the fibers were 700 mJ and 220 mJ, respectively.
Improved index-matching of the trunk fiber and fiber tip at 2.94 microm resulted in higher transmission and damage thresholds for the germanium oxide/sapphire fibers. The germanium oxide/sapphire fiber may represent a promising mid-infrared optical fiber delivery system for use in endoscopic applications of the Er:YAG laser requiring a flexible, biocompatible, and robust fiber delivery system for contact tissue ablation.
由于缺乏合适的光纤传输系统,铒钇铝石榴石(Er:YAG)激光的内镜应用受到限制。本研究的目的是比较Er:YAG激光辐射通过带有二氧化硅和蓝宝石光纤尖端的氧化锗主干光纤的传输情况,以探讨其在内镜检查中用于接触组织消融的潜力。
研究设计/材料与方法:波长为2.94微米、脉冲长度为300微秒、脉冲能量为5至1360毫焦、耦合到3至10赫兹脉冲重复率的Er:YAG激光辐射,通过1米长的氧化锗光纤传输,光纤带有1厘米长、直径550微米的二氧化硅或蓝宝石尖端。
氧化锗/蓝宝石光纤的传输率为65±5%,而氧化锗/二氧化硅光纤的传输率为55±4%(P<0.05)。混合光纤的损伤阈值平均分别为309±44毫焦和126±43毫焦(每组7根光纤)(P<0.05)。通过光纤传输的最高脉冲能量分别为700毫焦和220毫焦。
在2.94微米处主干光纤与光纤尖端的折射率匹配得到改善,使得氧化锗/蓝宝石光纤具有更高的传输率和损伤阈值。氧化锗/蓝宝石光纤可能是一种有前景的中红外光纤传输系统,可用于Er:YAG激光的内镜应用,这种应用需要一种灵活、生物相容且坚固的光纤传输系统来进行接触组织消融。