Lichy Christoph, Grau Armin J
University of Heidelberg Im Neuenheimer Feld, Department of Neurology, 400, 69120 Heidelberg, Germany.
Expert Rev Vaccines. 2006 Aug;5(4):535-40. doi: 10.1586/14760584.5.4.535.
Acute infections, mainly of the respiratory tract, have consistently been demonstrated to considerably increase the risk of stroke. At present, prospective interventional trials are lacking and there is no proof of the effectiveness of any therapeutic anti-infective strategy in stroke prevention. However, some new evidence from observational studies lends support to the idea that influenza vaccination may contribute importantly to fighting stroke. Although final proof of efficacy is still missing, patients with previous cerebral ischemia and subjects of any age at high risk of stroke should be encouraged to receive annual influenza vaccination.
主要为呼吸道的急性感染一直被证实会显著增加中风风险。目前，缺乏前瞻性干预试验，且尚无证据表明任何抗感染治疗策略在预防中风方面有效。然而，观察性研究的一些新证据支持了流感疫苗接种可能对预防中风有重要作用这一观点。尽管仍缺乏疗效的确切证据，但既往有脑缺血病史的患者以及任何年龄的中风高危人群都应被鼓励每年接种流感疫苗。
