Kontakis George M, Tossounidis Theodoros, Weiss Kurt, Pape Hans-Christoph, Giannoudis Peter V
University Hospital of Heraklion, Crete, Greece.
Injury. 2006 Oct;37 Suppl 4:S19-24. doi: 10.1016/j.injury.2006.08.037.
Few data are available in the literature regarding fat embolism in cases of bilateral femoral and pathological femoral fractures. The incidence of bilateral femoral fractures ranges from 2-9.5% of the total number of patients with femoral fractures, and they usually occur in high energy trauma and multi-trauma patients. Although injury severity scores tend to underestimate the severity of these injuries, fat embolism seems to occur in increased frequency ranging from 4.8-7.5%. Intramedullary nailing, which is the preferred surgical treatment, triggers a systemic inflammatory response that poses an additional burden to pulmonary function. In addition, the femur is a common site of metastatic bone disease. The treatment of impending and actual pathological fractures is complicated by increased rates of lung damage due to various factors. Fat embolism during treatment--mainly with intramedullary nails--generally seems to range from 0-10%.
关于双侧股骨骨折和病理性股骨骨折病例中的脂肪栓塞,文献中可用的数据很少。双侧股骨骨折的发生率占股骨骨折患者总数的2%-9.5%,通常发生在高能创伤和多发伤患者中。尽管损伤严重程度评分往往低估了这些损伤的严重程度,但脂肪栓塞的发生率似乎有所增加,范围在4.8%-7.5%。髓内钉固定是首选的手术治疗方法,它会引发全身炎症反应,给肺功能带来额外负担。此外,股骨是转移性骨病的常见部位。由于各种因素导致肺损伤率增加,使得即将发生和实际的病理性骨折的治疗变得复杂。治疗期间(主要是使用髓内钉)的脂肪栓塞发生率一般似乎在0%-10%之间。