Gagnon Fabien, Duchesne Jean-François, Lévesque Benoît, Gingras Suzanne, Chartrand Josée
Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Canada.
Int J Environ Health Res. 2006 Oct;16(5):349-59. doi: 10.1080/09603120600869265.
Consumption of untreated, inadequately treated or simply chlorinated water has been the source of a number of giardiasis epidemics. The aim of this study was to verify if water supply is associated with giardiasis in an endemic context. We conducted a case-control study that included 139 cases and 417 control subjects. To assess risk associated to water consumption, we calculated odds ratios (OR) using "source of water" and "presence and type of filtration" as criteria. A logistic regression model was used to control other risk factors. In children aged 1 - 13, the only significant risk factor was the consumption of at-risk tap water (i.e., filtered or unfiltered surface water or unfiltered shallow well water; OR = 6.13). In people aged 14 - 64, the consumption of this water was not a risk factor for the disease. The divergence in results between age groups could be explained by acquired immunity.
饮用未经处理、处理不当或仅经过氯化处理的水一直是许多贾第虫病疫情的源头。本研究的目的是验证在地方病流行背景下，供水是否与贾第虫病有关。我们开展了一项病例对照研究，纳入了139例病例和417名对照对象。为评估与水消费相关的风险，我们以“水源”和“过滤的存在及类型”为标准计算比值比（OR）。使用逻辑回归模型来控制其他风险因素。在1至13岁的儿童中，唯一显著的风险因素是饮用有风险的自来水（即过滤或未过滤的地表水或未过滤的浅井水；OR = 6.13）。在14至64岁的人群中，饮用这种水并非该疾病的风险因素。年龄组之间结果的差异可以用获得性免疫来解释。
