Krafft W, König E M, Schirmer A, Müller U
Arbeitsgruppe Tumorchemotherapie in der Gynäkologie der DDR.
Zentralbl Gynakol. 1990;112(12):767-71.
Doubtlessly the exploration of the peritoneal cavity is essential for the determination of the efficacy of cis platine chemotherapy in ovarian cancer. Second-look operation and second-look laparoscopy are established as diagnostic methods. In a follow up study containing 92 patients with CR after cis platine chemotherapy it has been evident that the remission time is independent on the kind of invasive diagnostic methods. In contrast to these results the noninvasive diagnostic methods (like CT or X ray in 19 pat.) survival time was 20 months. The difference to both other groups is significant. Therefore it is necessary in cases with complete response to secure the results invasively, but a second-look operation is not compulsary.
毫无疑问，对于确定顺铂化疗在卵巢癌中的疗效而言，腹腔探查至关重要。二次探查手术和二次探查腹腔镜检查已成为诊断方法。在一项对92例顺铂化疗后达到完全缓解（CR）的患者的随访研究中，很明显缓解时间与侵入性诊断方法的类型无关。与这些结果形成对比的是，非侵入性诊断方法（如19例患者采用的CT或X线检查）的生存时间为20个月。与其他两组的差异具有显著性。因此，对于完全缓解的病例，有必要通过侵入性手段来确证结果，但二次探查手术并非必需。
