Pinsolle Vincent, Grinfeder Christophe, Mathoulin-Pelissier Simone, Faucher Alain
Service de Chirurgie Plastique CHU Bordeaux/Université Bordeaux 2, Hopital Pellegrin Tondu, Place Amelie Raba-Leon, 33076 Bordeaux Cedex, France.
J Plast Reconstr Aesthet Surg. 2006;59(10):1017-24. doi: 10.1016/j.bjps.2006.03.057. Epub 2006 Jun 5.
The purpose of this study was to describe the complications of immediate breast reconstruction, to compare their rates with respect to the surgical procedure and to patient's characteristics, in order to improve surgical indications and patient information. We carried out a retrospective study of 266 immediate breast reconstructions (249 women) over a 12-year period (latissimus dorsi myocutaneous flap with implant 61%, autologous latissimus dorsi myocutaneous flap 15%, subpectoral implant 24%). Mean age was 48 and the median follow-up was seven years (2-14). The overall complication rate was 49% (128), and there were 10 reconstruction failures. The most frequent complications were dorsal seroma 26% (70), capsular contracture 10% (27), skin necrosis 8.3% (22), and haematoma 5.6% (15). The complication rate for immediate breast reconstruction with implant alone (39%) was lower than that associated with latissimus dorsi with or without implant (51%), but the difference was not significant (Chi-square: p=0.07). The risk factors for complications were smoking (skin necrosis, Fisher: p=0.02), obesity (infection, Fisher: p=0.004), and radiotherapy (capsular contracture, Chi-square: p=2.6 x 10(-5)). Smoking was found as the only risk factor of reconstruction failure (Fisher: p=0.015). Capsular contractures were more frequent when implants were used alone (25%) as well as when used along with a flap (6.8%) (Chi-square: p=2 x 10(-5)). Infections were also higher in the non-flap group than in the flap group (Fisher: p=0.02). In our opinion, latissimus dorsi myocutaneous flap with or without an implant is a good compromise between complication risk and necessity of good cosmetic result requirement. These results have led us to delay or contraindicate reconstruction in the case of obesity or heavy smoking. In the case of probable post-operative radiotherapy, we prefer to delay the breast reconstruction.
本研究的目的是描述即刻乳房重建的并发症,比较其在手术方式和患者特征方面的发生率,以改善手术指征并为患者提供更全面的信息。我们对266例即刻乳房重建手术(涉及249名女性)进行了一项回顾性研究,研究时间跨度为12年(背阔肌肌皮瓣联合植入物占61%,自体背阔肌肌皮瓣占15%,胸大肌下植入物占24%)。平均年龄为48岁,中位随访时间为7年(2 - 14年)。总体并发症发生率为49%(128例),有10例重建失败。最常见的并发症是背部血清肿,发生率为26%(70例),包膜挛缩为10%(27例),皮肤坏死为8.3%(22例),血肿为5.6%(15例)。单纯植入物即刻乳房重建的并发症发生率(39%)低于背阔肌肌皮瓣联合或不联合植入物的情况(51%),但差异无统计学意义(卡方检验:p = 0.07)。并发症的危险因素包括吸烟(皮肤坏死,Fisher检验:p = 0.02)、肥胖(感染,Fisher检验:p = 0.004)以及放疗(包膜挛缩,卡方检验:p = 2.6×10⁻⁵)。吸烟被发现是重建失败的唯一危险因素(Fisher检验:p = 0.015)。单独使用植入物时包膜挛缩更为常见(25%),与皮瓣联合使用时也有一定比例(6.8%)(卡方检验:p = 2×10⁻⁵)。非皮瓣组的感染发生率也高于皮瓣组(Fisher检验:p = 0.02)。我们认为,背阔肌肌皮瓣联合或不联合植入物在并发症风险和良好美容效果需求之间是一个较好的折衷方案。这些结果使我们在肥胖或重度吸烟的情况下延迟或禁忌进行重建。在可能进行术后放疗的情况下,我们更倾向于延迟乳房重建。