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[青少年血管瘤的医学治疗]

[Medical treatment of juvenile hemangiomas].

作者信息

Boon L-M, Bataille A-C, Bernier V, Vermylen C, Verellen G

机构信息

Service de chirurgie plastique, centre des anomalies vasculaires, cliniques universitaires Saint-Luc, 10, avenue Hippocrate, 1200 Bruxelles, Belgique.

出版信息

Ann Chir Plast Esthet. 2006 Aug-Oct;51(4-5):310-20. doi: 10.1016/j.anplas.2006.07.004. Epub 2006 Sep 25.

DOI:10.1016/j.anplas.2006.07.004
PMID:16997446
Abstract

Infantile hemangioma always involute in 5 to 7 years. However, 10% of proliferating hemangiomas will necessitate a therapeutic approach, often medical, in order to avoid life or organ threatening, fonctional or esthetic sequelae. "Which hemangioma need to be treated, when and how" are important questions for the optimal management of infantile hemangiomas. Corticotherapy is still the treatment of choice for these lesions. Other anti-angiogenic molecules have also been successfully used such as interferon alfa-2a and vincristine. This chapter tries to answer these questions and detail the different medical modalities for the treatment of infantile hemangioma.

摘要

婴儿血管瘤通常在5至7岁时自行消退。然而,10%的增殖期血管瘤需要采取治疗措施,通常是药物治疗,以避免危及生命或器官、功能或美观方面的后遗症。“哪些血管瘤需要治疗、何时治疗以及如何治疗”是婴儿血管瘤最佳管理中的重要问题。皮质类固醇疗法仍是这些病变的首选治疗方法。其他抗血管生成分子,如干扰素α-2a和长春新碱,也已成功应用。本章试图回答这些问题,并详细介绍治疗婴儿血管瘤的不同药物治疗方法。

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1
[Medical treatment of juvenile hemangiomas].[青少年血管瘤的医学治疗]
Ann Chir Plast Esthet. 2006 Aug-Oct;51(4-5):310-20. doi: 10.1016/j.anplas.2006.07.004. Epub 2006 Sep 25.
2
[Infantile hemangioma].[婴儿血管瘤]
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Recombinant interferon alfa-2b in the treatment of vision-threatening capillary hemangiomas in childhood.
J AAPOS. 1997 Dec;1(4):226-30. doi: 10.1016/s1091-8531(97)90042-2.
4
[Vincristine treatment for function- and life-threatening infantile hemangioma].[长春新碱治疗功能及生命威胁性婴儿血管瘤]
Arch Pediatr. 2004 Feb;11(2):99-107. doi: 10.1016/j.arcped.2003.10.014.
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[Vincristine treatment for management of alarming hemangiomas in infancy].[长春新碱治疗婴儿期危险型血管瘤]
Rev Med Liege. 2008 Jan;63(1):14-7.
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Diffuse infantile hepatic hemangiomas: a report of four cases successfully managed with medical therapy.弥漫性婴儿肝血管瘤:4例药物治疗成功病例报告
Pediatr Dermatol. 2011 May-Jun;28(3):267-75. doi: 10.1111/j.1525-1470.2011.01421.x. Epub 2011 Apr 26.
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Propranolol versus corticosteroids: what should be the treatment of choice in infantile hemangiomas?普萘洛尔与皮质类固醇:婴儿血管瘤的首选治疗方法应该是什么?
Ann Plast Surg. 2015 Feb;74(2):237-41. doi: 10.1097/SAP.0b013e318299cd4e.
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Current treatments for infantile hemangiomas.
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[Angioma of the lip in pediatric age].
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Current treatment and management of infantile hemangiomas.婴幼儿血管瘤的当前治疗和管理。
Surv Ophthalmol. 2019 Sep-Oct;64(5):608-618. doi: 10.1016/j.survophthal.2019.02.005. Epub 2019 Feb 14.

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[Medication-based therapy of infantile hemangioma and lymphatic malformations].[婴儿血管瘤和淋巴管畸形的药物治疗]
HNO. 2014 Jan;62(1):12-8. doi: 10.1007/s00106-013-2794-0.