Boon L-M, Bataille A-C, Bernier V, Vermylen C, Verellen G
Service de chirurgie plastique, centre des anomalies vasculaires, cliniques universitaires Saint-Luc, 10, avenue Hippocrate, 1200 Bruxelles, Belgique.
Ann Chir Plast Esthet. 2006 Aug-Oct;51(4-5):310-20. doi: 10.1016/j.anplas.2006.07.004. Epub 2006 Sep 25.
Infantile hemangioma always involute in 5 to 7 years. However, 10% of proliferating hemangiomas will necessitate a therapeutic approach, often medical, in order to avoid life or organ threatening, fonctional or esthetic sequelae. "Which hemangioma need to be treated, when and how" are important questions for the optimal management of infantile hemangiomas. Corticotherapy is still the treatment of choice for these lesions. Other anti-angiogenic molecules have also been successfully used such as interferon alfa-2a and vincristine. This chapter tries to answer these questions and detail the different medical modalities for the treatment of infantile hemangioma.
婴儿血管瘤通常在5至7岁时自行消退。然而,10%的增殖期血管瘤需要采取治疗措施,通常是药物治疗,以避免危及生命或器官、功能或美观方面的后遗症。“哪些血管瘤需要治疗、何时治疗以及如何治疗”是婴儿血管瘤最佳管理中的重要问题。皮质类固醇疗法仍是这些病变的首选治疗方法。其他抗血管生成分子,如干扰素α-2a和长春新碱,也已成功应用。本章试图回答这些问题,并详细介绍治疗婴儿血管瘤的不同药物治疗方法。